Ethnobotanical survey of medicinal plants used to manage High Blood Pressure and Type 2 Diabetes Mellitus in Bitterfontein, Western Cape Province, South Africa

Davids, Denver; Gibson, Diana; Johnson, Quinton

doi:10.1016/j.jep.2016.10.063

Cited by 47 publications

(30 citation statements)

References 80 publications

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“…The demographic information of selected informant’s data shows that males (55%) dominates in the traditional knowledge compared to 45% of females. Contrarily, other authors reported the females to dominate in the traditional knowledge [ 31 , 32 ].…”

Section: Discussionmentioning

confidence: 99%

Ethnobotanical knowledge of the lay people of Blouberg area (Pedi tribe), Limpopo Province, South Africa

Mongalo

Makhafola

2018

J Ethnobiology Ethnomedicine

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BackgroundLimpopo province, South Africa, has a rich plant diversity and is referred to as one of the hotspots areas within the country. The aim of the current work was to identify and document medicinal plant species used by the indigenous Pedi people of Blouberg area, Limpopo Province, South Africa.MethodsA total of 40 informants which includes both traditional healers and medicinal plant sellers were randomly selected and asked about the plant species used in treatment of variety of infections using a structured questionnaire. Follow-up visits and various field walks were also used to identify and document various plant species used in Traditional medicine (TM). The interviews were carried out from April 2008 to June 2016 using indigenous language (Sehananwa).ResultsA total of 82 medicinal plants species belonging to 42 families have been collected, identified and documented. About 46.34% of the plant species were herbs, followed by trees (25.61%), shrubs (20.73%) and climbers (7.32%). The most used plant parts are roots and rhizomes (58.58%). Peltophorum africanum Sond revealed frequency index of greater than 70 and is used in combination with other plants species to treat various pathogenic infections. Most of the plant species reported are used in the treatment of sexually transmitted infections (24), management of HIV-AIDS (15) and stomach ache (14). Our informants indicated that the use of plant medicines in combinations is also applied to cure pathogenic infections.ConclusionThe current study demonstrate that the indigenous people of Blouberg area, Limpopo Province harbours an important information about the vegetation around them. The plant species are used in the treatment of various pathogenic infections, offers fruits as additional source of food and form integral part of other medicinal products that may in turn produce income.

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Section: Discussionmentioning

confidence: 99%

Ethnobotanical knowledge of the lay people of Blouberg area (Pedi tribe), Limpopo Province, South Africa

Mongalo

Makhafola

2018

J Ethnobiology Ethnomedicine

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“…This plant, among the other 29 Tulbaghia species, is endemic to southern Africa particularly SA (Eastern Cape, KZN, Limpopo) and Zimbabwe, with various indigenous applications. It is used as an aphrodisiac, as well as to treat sinus conditions, headaches, cough, colds, asthma, tuberculosis (pulmonary), intestinal worms, HTN, and cancer of the esophagus [24,27,29,30,33], owing to its numerous pharmacological and biological properties. Besides the fact that it possesses sulfur-containing compounds (e.g., alliin), showing much resemblance to Allium ursinum (Amaryllidaceae) Linn.…”

Section: Stangeria Eriopus (Kunze) Baillmentioning

confidence: 99%

A Review of Plants Used in South African Traditional Medicine for the Management and Treatment of Hypertension

Balogun

Ashafa

2018

Planta Med

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South Africa contains 9% of the worldʼs higher plants, and despite its rich biodiversity, it has one of the highest prevalence of hypertension in Africa. This review provides information on medicinal plants embraced in South Africa for hypertension management, with the aim of reporting pharmacological information on the indigenous use of these plants as antihypertensives. This review not only focuses on the activity of antihypertensive medicinal plants but also reports some of its phytochemical constituents and other ethnopharmacological and therapeutic properties. Information obtained from scientific and or unpublished databases such as Science Direct, PubMed, SciFinder, JSTOR, Google Scholar, Web of Science, and various books revealed 117 documented antihypertensive plant species from 50 families. Interestingly, Asteraceae topped the list with 16 species, followed by Fabaceae with 8 species; however, only 25% of all plant species have demonstrated antihypertensive effects originating from both in vitro and in vivo studies, lending credence to their folkloric use. Only 11 plant species reportedly possess antihypertensive properties in animal models, with very few species subjected to analytical processes to reveal the identity of their bioactive antihypertensive compounds. In this review, we hope to encourage researchers and global research institutions (universities, agricultural research councils, and medical research councils), particularly those showing an interest in natural products, for the need for concerted efforts to undertake more studies aimed at revealing the untapped potential of these plants. These studies are very important for the development of new pharmaceuticals of natural origin useful for the management of hypertension.

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“…Plants have been used by millions of people as a source of food and for medicinal purposes for thousands of years [2,5]. An estimated 80% of the world's population and 80% of black South Africans still rely on traditional medicine for their primary health care needs [6]. Traditional medicine has not only gained popularity due to its effectiveness against diseases but because sometimes it is the only therapy that is available in rural areas in the context of developing countries [7].…”

Section: Introductionmentioning

confidence: 99%

Disruption of microbial cell morphology by Buxus macowanii

Ngobeni

Mashele

Malebo

et al. 2020

BMC Complement Med Ther

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Background: Microbial infections are one of the major causes of death globally. This is attributed to the rising costs of primary healthcare and its inaccessibility especially in developing countries. Moreover, there has been an increase in microbial strains that have reduced susceptibility to antimicrobial drugs. Research on the antimicrobial properties of medicinal plants, which could address these problems, has become more important as they present fewer side effects when compared to the antibiotics currently in use. This study evaluated the antimicrobial properties of a methanolic extract from Buxus macowanii in order to assess its potential in the development of novel antimicrobial drugs. Methods: Antimicrobial activity of the extract was evaluated using the broth microdilution method. The effects of B. macowanii on the morphology of B. cereus were observed using Scanning and Transmission electron microscopy. Chemical profiling of the plant extract was performed using the GCMS. Results: The extract showed antimicrobial activity against all the microbial species used. Microscopic examination of the cells of B. cereus cells treated with Buxus macowanii showed some changes in morphology such as damage of the cell wall, swelling of the cells and incomplete cell division that eventually resulted in cell death. Neophytadiene, an antimicrobial compound was detected in the extract using GCMS. Conclusion: The morphological disruptions of the cell wall of Bacillus cereus explain the antimicrobial properties of B. macowanii and indicate its possible application in the development of natural antimicrobial drugs.

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Ethnobotanical survey of medicinal plants used to manage High Blood Pressure and Type 2 Diabetes Mellitus in Bitterfontein, Western Cape Province, South Africa

Cited by 47 publications

References 80 publications

Ethnobotanical knowledge of the lay people of Blouberg area (Pedi tribe), Limpopo Province, South Africa

Ethnobotanical knowledge of the lay people of Blouberg area (Pedi tribe), Limpopo Province, South Africa

A Review of Plants Used in South African Traditional Medicine for the Management and Treatment of Hypertension

Disruption of microbial cell morphology by Buxus macowanii

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