Ethnomedicinal survey of medicinal plants used in the management of sickle cell disorder in Southern Nigeria

Amujoyegbe, O.O.; Idu, MacDonald; Agbedahunsi, Joseph M.; Erhabor, Joseph O.

doi:10.1016/j.jep.2016.03.042

Cited by 47 publications

(29 citation statements)

References 30 publications

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“…The predominance of taxa in the Fabaceae family corroborates observations of Ngene et al [43] (Cameroon), Amujoyegbe et al [44] (Nigeria) and Ong et al [45] (India and Bangladesh). The medicinal use of taxa of this family can probably be explained by the bioactive elements they contain, including tannins, alkaloids, coumarins, steroids, saponosides, flavonoids and isoflavonoids [46].…”

Section: Medicinal Plant Usesupporting

confidence: 89%

Ethnobotanical Characterization of Medicinal Plants Used in Kisantu and Mbanza-Ngungu Terroirs, Kongo-Central Province in DR Congo

Kembelo

Bakwaye

Katula

et al. 2020

Preprint

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Background: The phytotherapeutic knowledge of the Kongo people in the terroirs of Kisantu and Mbanza-Ngungu in Kongo-Central Province (DR Congo) is rapidly eroding. To document the remaining knowledge, we conducted an ethnobotanical survey on the most important medicinal plant species and diseases treated with them, as well as plants with therapeutic potential. We also verified how medicinal knowledge differs between different social groups.Method: From June 2017 until February 2018 and from February until April 2019, we conducted a survey with 188 phytotherapists, selected using the snowball method and surveyed using semi-structured interviews. Voucher specimens were taken for identification. Ethnobotanical database was analyzed using medicinal Use Value (UVs), Informant Agreement Ratio (IARs), Informant Consensus Factor (ICF) and Species Therapeutic Potential (STP). Medicinal knowledge between different social groups was analyze using non parametric tests and the Poisson regression. Results: A total of 231 plants (i.e. 227 botanical species, representing 192 genera and 79 families) were reportedly used to treat 103 diseases. Most abundant taxa were reported for the Fabaceae family (11.9 %) and genus Solanum (1.8%). Most harvested species (45,0%) were from anthropized areas. Most frequent plant part, botanical form, preparation and administration method were leaves (39.4%), herbs (37.1%), decoction (41.7%) and oral ingestion (72%) respectively. Four of all inventoried species showed high UV S (> 0.05), whereas 8 had an IAR of 1. According to respondent consensus on plant use, 31 diseases were mentioned. Highest ICF (≥ 0,4) were observed for hemorrhoids (0.44), amoebiasis (0.43) and itchy rash (0.42). Fifty-four plant species were identified likely to have interesting therapeutic potential. Analysis of medicinal knowledge showed that the mean number of reported species and diseases vary considerably depending on gender, type and location of therapists (P < 0.05). Conclusion: Results prove that the Kongo phytopharmacopoeia makes use of interesting medicinal plant species that could be further studied for conservation and pharmacological applications.

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Section: Medicinal Plant Usesupporting

confidence: 89%

Ethnobotanical Characterization of Medicinal Plants Used in Kisantu and Mbanza-Ngungu Terroirs, Kongo-Central Province in DR Congo

Kembelo

Bakwaye

Katula

et al. 2020

Preprint

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“…β-sitosterol (8) is also reported in alcoholic extract of A. Javanica's flower [76]. In another study compound 9, stigmasterol-3-glyceryl-2'-linoleate (10) and campesterol (11) were also isolated from the extract of aerial parts of A. lanata [84]. Compound 8 and 11 are also reported from A. javanica var.…”

Section: Phyto-constituents Isolated Fromaerva Plantsmentioning

confidence: 99%

Pharmaceutical, Ethnopharmacological, Phytochemical and Synthetic Importance of Genus Aerva: A Review

Musaddiq

Mustafa

Ahmad

et al. 2018

Natural Product Communications

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Aerva plants are known widely for their exceptional medicinal uses. They have been employed conventionally for their medicinal properties by the common folk in several regions of the world. This indicates the efficacy of these remarkable herbs. They are also known for their multiple biological activities such as antioxidant, antibacterial, antilithiatic, hepatoprotective, antidiabetic, anticancer, antihyperlipidemic and nephroprotective potential. These pharmacological actions are associated with the presence of valuable nutrients and biochemical compounds such as sterols/terpenes, flavonoids, alkaloids, phenolics and sugars. The proper utilization of the substances obtained from these plants can enhance the finesse of the capabilities of these plants. These plants are not only medicinally important but are significantly serving several other scientific purposes. In the prospect of medicinal, scientific uses and the bioavailability of precious chemicals of Aerva species, a comprehensive review is compiled, which focuses on the detailed profile of biochemical compounds, pharmacological functions and biological activities of Aerva plants. The review also discusses the synthetic importance and the toxicity of these plants. The study aims to compile comprehensively what is already done and what more is needed to be done in the future investigations related to Aerva species.

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“…Also this extracts can use in treatment leukemia and sickle cell disorder [6]- [8]. Also The studies showed the extracts of the different plants can be use to treat cancer-like symptoms [9].…”

Section: Introductionmentioning

confidence: 98%

The Effects of Scrophularia striata Extract on HEK Cell Line in Cell Culture

2016

2016 International Conference on Biological and Environmental Science (BIOES-16) June 8-9, 2016 New Jersey (USA)

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Ethnomedicinal survey of medicinal plants used in the management of sickle cell disorder in Southern Nigeria

Cited by 47 publications

References 30 publications

Ethnobotanical Characterization of Medicinal Plants Used in Kisantu and Mbanza-Ngungu Terroirs, Kongo-Central Province in DR Congo

Ethnobotanical Characterization of Medicinal Plants Used in Kisantu and Mbanza-Ngungu Terroirs, Kongo-Central Province in DR Congo

Pharmaceutical, Ethnopharmacological, Phytochemical and Synthetic Importance of Genus Aerva: A Review

The Effects of Scrophularia striata Extract on HEK Cell Line in Cell Culture

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