Ethnopharmacological review of vinca plant for anticancer activity

Abstract

The strive of this assessment shows that Vinca rosea, many obviously grown vegetation round us which can be used for medicinal purposes. It has many known names like vinca Rosea, Madagascar periwinkle, vibrant eyes, Cape periwinkle, graveyard plant, old maid, crimson periwinkle, rose periwinkle myrtle. Ayurveda is the Indian conventional device of medication which focuses on the scientific capability of plant life. Catharanthus roseus is one plant recognized nicely in Ayurveda. It is known for its antitumour, anti-diabetic, anti-microbial, anti-oxidant and antimutagenic effects. It is an evergreen plant first originated from islands of Madagascar. The flowers can also range in color from red to pink and leaves are organized in opposite pairs. It produces nearly 130 alkaloids especially ajmalcine, vinceine, resperine, vincristine, vinblastine and raubasin. Vincristine and vinblastine are used for the treatment of various types of cancer such as Hodgkin’s disease, breast cancer, skin cancer and lymphoblastic leukemia. It has high medicinal values which need to be explored considerably. This ethnopharmacological review deals with anticancer activities and pharmacognostic study of Vinca plant.

Cytotoxicity of Fractions of Dracontium spruceanum Chloroform Extract in MDA-MB-231 and MCF-7 Breast Cancer Cell Lines

“…Studies have shown that flavonoids such as genistein, epigallocatechin, and resveratrol can stop the progression and prevent future metastasis of breast cancer (8). Currently, several chemotherapeutic drugs are isolated from natural products, such as vinblastine and vincristine derived from the plant Catharanthus roseus (9).…”