Ethnopharmacological survey of plants used for the treatment of female infertility in Baham, Cameroon

Invasive fungal infections are important causes of mortality despite advances in antifungal therapy. The aim of this study was collect information on plants used by traditional healers for the treatment of fungal infections in the Baham subdivision (Western region of Cameroon) and to assess the in vitro antifungal and antioxidant potentials of the extracts from the medicinal plants surveyed. The antifungal activity was assessed by the broth micro-dilution method and the antioxidant activity was determined using the free-radical scavenging assays. The extracts for the plants Kotschya strigosa and Eryngium foetidum had potent antifungal activity with minimum inhibitory concentration value of 32 µg/mL against Cryptococcus neoformans. Eugenia gilgii extract had the highest free radical scavenging capacity in 2,2-Diphenyl-1-picrylhydrazyl assay (IC 50 of 4.54μg/mL). There is a rich wealth of knowledge and usage of plants by traditional healers for the treatment of fungal infections and further studies should consider isolation of active compounds from the extracts in order to assess the potential for developing new, effective, safe and affordable phytomedicine for the treatment of fungal infections and other pharmacological applications.

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“…These observations prove the reliability of information gathered during this survey. This is also consistent with other previous studies 9 .…”

Section: Ethnobotanical Surveysupporting

confidence: 94%

Ethnopharmacological survey, antioxidant and antifungal activity of medicinal plants traditionally used in Baham locality (Cameroon) to treat fungal infections

Tchuenguem¹,

Kechia²,

Kuiaté³

et al. 2017

Arch Med Biomed Res

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“…However, this might only be valid if the chemistry of the roots or bark is similar to that of the leaves. There are several communities in Africa and elsewhere who are mainly using leaves to treat a variety of ailments, examples are Burkina Faso (Nadembega et al, 2011), Cameroon (Telefo et al, 2011) 3.4. Preparation, dosage and route of administration of the remedy.…”

Section: Plant Species and Their Familiesmentioning

confidence: 99%

The traditional use of plants to manage candidiasis and related infections in Venda, South Africa

Masevhe

McGaw

Eloff

2015

Journal of Ethnopharmacology

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Ethnopharmacological relevance: This paper presents results of an ethnobotanical survey of medicinal plants used for the management of candidiasis and related fungal infections in the Venda area, South Africa. Materials and Methods:Ethnobotanical data about the uses of plants were gathered from eleven rural traditional healers using semi-structured interviews.Results: A total of 45 species belonging to 24 different families were identified, of which the dominant family was the Fabaceae with 13 species (28.9%) followed by the Asteraceae and Solanaceae with 3 species each (6.7 %). A total of 28 of these plant species (62.2%) have been shown to have anticandidal activity and 14 species (31%) have been recorded for antifungal uses in the literature. Amongst the 45 species recorded, 51% were trees, 33% were shrubs, and 16% were herbs. The most widely used plant species were Acacia caffra, Clerodendrum glabrum, Croton gratissimus, Elaeodendron transvaalense, Faurea saligna, Hippocratea longipetiolata, Osyris lanceolata, Richardia brasiliensis, Schkuhria pinnata, Schotia brachypetala, Spilanthes acmella, Strychnos potatorum, Vangueria infaustasubsp. infausta and Withania somnifera. The plant parts mostly used in the therapeutic preparations were roots (27.7%), bark (23.2%), and a combination of roots, bark (18.7%) and leaves (14.3%). Decoctions (44.4%), infusions (20%), macerations (17.7%), burning (11.4%) and paste (6.5%) were used. Most of the herbal remedies were administered orally. The main factors threatening the conservation status of these plants are unsustainable methods of harvesting, logging for firewood, building materials and crafts. Conclusion:The Venda area is rich in plant diversity and local indigenous knowledge of medicinal plants can play an important role as a model for low cost primary health care. Further studies are in progress to validate the indigenous plants recorded as traditional remedies in this area.

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“…Leaves were often revealed in many ethnobotanical studies to be the most preferred part of plant for the preparation of remedies, followed by root and bark. This is probably because leaves are easy to collect compared with roots, flowers, and fruits (Giday et al 2009, Telefo et al 2011. This observation may also be due to the fact that leaves are the main photosynthetic organs containing photosynthates, which might be responsible for active principles (Bhattarai et al 2006).…”

Section: Plant Parts and Manner Of Usementioning

confidence: 99%

Diversity, Knowledge, and Use of Plants in Traditional Treatment of Diabetes in the Republic of Benin

Laleye¹,

Mensah

Assogbadjo

et al. 2015

Ethnobot. Res. App.

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Ethnopharmacological survey of plants used for the treatment of female infertility in Baham, Cameroon

Cited by 119 publications

References 36 publications

Ethnopharmacological survey, antioxidant and antifungal activity of medicinal plants traditionally used in Baham locality (Cameroon) to treat fungal infections

Ethnopharmacological survey, antioxidant and antifungal activity of medicinal plants traditionally used in Baham locality (Cameroon) to treat fungal infections

The traditional use of plants to manage candidiasis and related infections in Venda, South Africa

Diversity, Knowledge, and Use of Plants in Traditional Treatment of Diabetes in the Republic of Benin

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