Ethnopharmacology of <i>Leonotis nepetifolia</i> (L.) R. Br., Lamiaceae, used to cure Jaundice and Liver Disorders by Baiga Tribe of Mandla District of Madhya Pradesh

Ajuga orientalis L. is a member of the Lamiaceae family. Many biological properties of A. orientalis, such as antibacterial, anticancer, antioxidant, and anti-inflammatory activities, have been documented. The current study aims to assess the in vitro antidiabetic efficacy of aerial parts A. orientalis extracts through digestive enzymes inhibition assay (-amylase and -glucosidase), which are responsible for the digestion of poly and oligosaccharides. Acarbose, aqueous, and ethanolic extracts of A. orientalis were utilized in various concentrations (100, 200, 300, 400, and 500g/ml). The absorbance values for the enzymes -amylase and -glucosidase at 540nm and 400nm, respectively, were measured using a spectrophotometer. Both extracts demonstrated significant inhibition of α-amylase and α-glucosidase enzymes in a dose-dependent manner. Furthermore, the ethanolic extract showed more inhibitory activity than the aqueous extract. In conclusion, A. orientalis extracts exhibited in vitro antidiabetic activity.

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Ethnopharmacology of Leonotis nepetifolia (L.) R. Br., Lamiaceae, used to cure Jaundice and Liver Disorders by Baiga Tribe of Mandla District of Madhya Pradesh

Cited by 2 publications

References 0 publications

Botanical features and ethnopharmacological potential of Leonotis nepetifolia (L.) R. Br: a review

Botanical features and ethnopharmacological potential of Leonotis nepetifolia (L.) R. Br: a review

In vitro Assessment of the Antidiabetic Activity of Aqueous and Ethanolic Extracts from the Aerial Parts of Ajuga orientalis L.

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