Ethyl 1-(4-methoxyphenyl)-2-nitro-3-[4-oxo-3-phenyl-1-(4-methoxyphenyl)azetidin-2-yl]-2,3,10,10a-tetrahydro-1H,5H-pyrrolo[1,2-b]isoquinoline-10a-carboxylate

Abstract

In the mol­ecule of the title compound, C38H37N3O7, the pyrrolidine ring adopts a twist conformation and the six-membered heterocyclic ring has a boat conformation. In the crystal structure, mol­ecules are linked into a three-dimensional framework through inter­molecular C—H⋯O hydrogen bonds. One ethyl group is disordered over two positions with occupancies 0.67 (2)/0.33 (2).

2-{Hydroxy[1-(4-methoxyphenyl)-4-oxo-3-phenylazetidin-2-yl]methyl}acrylonitrile

“…The interplanar angle between the phenyl (C1-C6) and methoxy phenyl group (C10-C15) is 81.04 (9)°. The title compound exhibits structural similarities with the already reported related structures (Sundaresan et al, 2008, Kamala et al, 2008.…”

“…For the pharmacological properties of -lactam derivatives, see: Brakhage (1998). For related structures, see: Sundaresan et al (2008); Kamala et al (2008). For related geometrical parameters, see: Nizam Mohideen et al (2007).…”