Etiologic diagnosis of Capnocytophaga canimorsus meningitis by broad-range PCR

Capnocytophaga canimorsus Meningitis: Three Cases and a Review of the Literature

“…One article was excluded because it was in Danish and another article described a case that had been described elsewhere. For the review, 21 articles were used, describing 30 cases (Ofori‐Adjei et al., ; Chan and Fonseca, ; Carpenter et al., ; Imanse et al., ; Krol‐van Straaten et al., ; Blanche et al., ; Lion et al., ; Pers et al., ; Kampinga et al., ; Mendioroz et al., ; Le Moal et al., ; Biedermann and Deligne, ; Drouet et al., ; Gottwein et al., ; Meybeck et al., ; Risi and Spangler, ; de Boer et al., ; Gibou et al., ; Gasch et al., ; Monrad and Hansen, ; Popiel and Vinh, ). (Table S1 in Supporting information) We combined the cases identified in our cohort with the cases reported in the literature, describing a total of 33 cases of C. canimorsus meningitis.…”

Antimicrobial treatment of Capnocytophaga infections

“…Identification is performed by traditional biochemical testing used for the identification of oral Gramnegative species and by rapid determination of enzymatic reactions [3]. Molecular techniques have recently improved Capnocytophaga detection and identification [4][5][6].…”

A small ‘lick’ will sink a great ship: fulminant septicaemia after dog saliva wound treatment in an asplenic patient

“… Currently, a polymerase chain reaction (PCR) appears to be the most accurate method for diagnosis. Infection with C . canimorsus is treated primarily with penicillin, often combined with beta‐lactamase‐inhibitors as first‐line therapy, and clindamycin or imipenem is used as a second‐line option .…”

“…(16,17) Currently, a polymerase chain reaction (PCR) appears to be the most accurate method for diagnosis. (18,19) Infection with C. canimorsus is treated primarily with penicillin, often combined with beta-lactamase-inhibitors as first-line therapy, and clindamycin or imipenem is used as a second-line option. (20) Nevertheless, even in the case of rapid diagnosis and intensive care treatment, the fulminant course of infection may lead to limb and acral loss as amputation is warranted or even mortality in the immunocompromised patient.…”