Etiological Analysis of Initial Colonization of Periodontal Pathogens in Oral Cavity

Cortelli, José Roberto; Aquino, Davi Romeiro; Cortelli, Sheila Cavalca; Fernandes, Clovis Torres; Carvalho-Filho, Jonas de; Franco, Gilson César Nobre; Costa, Fernando Oliveira; Kawai, Toshihisa

doi:10.1128/jcm.02051-07

Cited by 72 publications

(73 citation statements)

References 36 publications

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“…48,49 Among these unclean surfaces many are colonized by bacteria since early childhood. 50 However, in the present survey only 27.3% of professionals stated that the cleaning of sites other than teeth and tongue was a reason to prescribe mouthrinses, which is inconsistent with scientific data. Therefore, additional efforts should be made to generalize this specific knowledge among dentists.…”

Section: Reasons For Mouthrinse Usecontrasting

confidence: 82%

Self-performed supragingival biofilm control: qualitative analysis, scientific basis and oral-health implications

Cortelli

Aquino

et al. 2010

Braz. oral res.

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Patients frequently fail to achieve an optimal mechanical plaque control. However, many patients are not confident about using mouthrinses, and many professionals refuse to prescribe them for regular daily use. Aiming at achieving a better understanding of the use and prescription of mouthrinses in periodontics, 24 dentists with different dental educational levels were purposively chosen and interviewed in a qualitative research. Partial data was presented at the 15th Congress of the Brazilian Association for Oral Health Promotion (ABOPREV), and full data was presented at the 88th General Session and Exhibition of the International Association for Dental Research (IADR). The professionals' answers were confirmed or rejected through scientific data analysis. Additionally, scientifically supported answers were provided for the interviewees' most frequent unanswered questions. Around half of the participants (46%) reported that they recommended the use of mouthrinses, although a high percentage (64%) of the dentists answered that they knew very little about the efficacy of mouthrinses and also about the oral benefits (54%) provided by them. All interviewees reported that they were aware of the fact that their patients, and themselves, failed to floss and, less frequently, to brush their teeth, and all of them believed that oral health impacts overall systemic health. Seventy five percent answered that using mouthrinses was safe. Most participants (55%) did not declare themselves as mouthrinse users. We concluded that dentists with different levels of dental education have only partial knowledge related to mouthrinse use in periodontics. The use of effective mouthrinses on a daily basis is justified and can help patients achieve or maintain a healthier mouth. A healthier mouth will positively impact patients' quality of life and could also benefit their overall systemic health

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Section: Reasons For Mouthrinse Usecontrasting

confidence: 82%

Self-performed supragingival biofilm control: qualitative analysis, scientific basis and oral-health implications

Cortelli

Aquino

et al. 2010

Braz. oral res.

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“…According to Kamma et al [21], 22-to 35-year-old smoking patients with early onset periodontitis harbored greater numbers of bacteria, mainly anaerobes such as P. gingivalis and T. forsythia. However, Cortelli et al [43] found no correlation between smoking and the prevalence of A. actinomycetemcomitans, P. gingivalis, T. forsythia, or P. intermedia. In our study, the duration and quantity of smoking as assessed using the pack-year data intensified the effect of smoking on the frequency of the positive bacterial samples in the girls.…”

Section: Discussionmentioning

confidence: 95%

Effect of teenage smoking on the prevalence of periodontal bacteria

et al. 2011

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The aim of our study was to investigate how teenage smoking affects the prevalence of periodontal bacteria and periodontal health with the hypothesis that smoking increases the prevalence of the bacteria. Oral health of 264 adolescents (15- to 16-year-olds) was clinically examined, and their smoking history was recorded. The participants also filled in a structured questionnaire recording their general health and health habits. Pooled subgingival plaque samples were taken for polymerase chain reaction analysis of Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Tannerella forsythia, Prevotella intermedia, Prevotella nigrescens, and Treponema denticola. The prevalence of P. intermedia (21% vs. 4%, p = 0.01) and T. forsythia and T. denticola (23% vs. 8%, p < 0.05, for both) was higher among female smokers than among non-smokers. T. forsythia and T. denticola were more often associated with bleeding on probing (29% vs. 12%; 25% vs. 10%, respectively) and deep pockets (25% vs. 15%; 23% vs. 10%, respectively) with smokers than non-smokers. Among the girls, a significant association was found between pack-years and the prevalence of P. nigrescens (p < 0.007). In both genders, A. actinomycetemcomitans and P. gingivalis were rare in this study. To conclude, periodontal bacteria were associated with higher periodontal index scores among all teenage smokers. Smoking girls harbored more frequently certain periodontal bacteria than non-smokers, but this was not seen in boys. Hence, our study hypothesis was only partly confirmed.

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“…Pooled subgingival samples were taken from five periodontal sites (> PD) 20 . Each selected tooth was isolated with sterile cotton rolls and the supragingival plaque was removed with sterile cotton pellets.…”

Section: Microbiological Examinationmentioning

confidence: 99%

Salivary and microbiological parameters of chronic periodontitis subjects with and without type 2 diabetes mellitus: a case-control study

Cortelli

Pinheiro

Costa

et al. 2014

Rev. odontol. UNESP

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ResumoIntrodução: Diversos estudos têm investigado as diferenças dos parâmetros salivares e microbianos entre pacientes diabéticos e não diabéticos, contudo, diferenças específicas ainda não estão claras, principalmente devido aos efeitos de variáveis de confusão. Objetivo: O objetivo deste estudo caso-controle foi avaliar os parâmetros salivares e microbianos de indivíduos com doença periodontal crônica com ou sem diagnóstico de diabetes melito tipo 2. Material e método: Este estudo caso-controle incluiu 60 indivíduos com periodontite crônica, 30 diabéticos (casos) e 30 não diabéticos (controles), pareados pela severidade da doença periodontal, gênero e idade. Saliva total estimulada foi coletada de todos os voluntários para mensuração do pH salivar e fluxo salivar. Amostras bacterianas foram coletadas com pontas de papel absorvente dos sítios periodontais com maior profundidade de sondagem e perda de inserção clínica. A frequência de A. actinomycetemcomitans, P. intermedia, P. gingivalis, T. forsythia e C. rectus foi avaliada por PCR. Os dados foram analisados estatisticamente pelo teste t de Student, Mann -Whitney e Qui-quadrado (p < 0,05). Resultado: Diabéticos apresentaram maior nível de glicose salivar e menor fluxo salivar em comparação aos não diabéticos. P. gingivalis e T. forsythia foram os patógenos mais frequentes (p < 0,05). Frequência bacteriana não diferiu entre os casos e controles. Conclusão: A condição diabetes influenciou o fluxo e os níveis de glicose salivar. Dentro da mesma severidade da periodontite crônica, indivíduos diabéticos não mostraram maior frequência de patógenos periodontais em comparação aos seus controles.Descritores: Saliva; bactérias; periodontite crônica; diabetes mellitus. AbstractBackground: Several studies have investigated the differences in salivary parameters and microbial composition between diabetic and non-diabetic patients, however, specific differences are still not clear mainly due to the effects of confounder. Aim: The aim of this case-control study was to evaluate the salivary and microbial parameters of chronic periodontitis subjects with and without type 2 diabetes mellitus. Material and method: This case-control study included 60 chronic periodontitis subjects, 30 diabetics (case group) and 30 non-diabetics (control group), paired according to periodontitis severity, gender and age. Stimulated whole saliva was collected from all volunteers to measure the salivary pH and the salivary flow rate. Bacterial samples were collected with paper points from periodontal sites showing the deepest periodontal pocket depth associated with the highest clinical attachment loss. The frequency of A. actinomycetemcomitans, P. intermedia, P. gingivalis, T. forsythia and C. rectus was evaluated by PCR. Data was statistically analyzed by Student's t, Mann-Whitney and Chi-square (p<0.05). Result: Diabetic subjects showed higher salivary glucose levels and lower stimulated flow rates in comparison to non-diabetic controls. P. gingivalis and T. forsythia were the most frequent pat...

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Etiological Analysis of Initial Colonization of Periodontal Pathogens in Oral Cavity

Cited by 72 publications

References 36 publications

Self-performed supragingival biofilm control: qualitative analysis, scientific basis and oral-health implications

Self-performed supragingival biofilm control: qualitative analysis, scientific basis and oral-health implications

Effect of teenage smoking on the prevalence of periodontal bacteria

Salivary and microbiological parameters of chronic periodontitis subjects with and without type 2 diabetes mellitus: a case-control study

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