Etiology and Complications of Refeeding Syndrome in the ICU

Leandro-Merhi, Vânia Aparecida; Aquino, José Luiz Braga de; Oliveira, Maria Rita Marques de

doi:10.1007/978-1-4614-7836-2_22

Cited by 2 publications

(6 citation statements)

References 49 publications

(87 reference statements)

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“…If so, then the tachycardia might have been an early sign of refeeding syndrome, indicative of fluid overload and cardiac failure. 37 Hence, in general, the hearts of patients in the WW2 studies might not have reached the advanced stage observed in patients with hunger cachexia, as documented in the studies from the Warsaw Ghetto.…”

Section: Heart Failurementioning

confidence: 98%

“…The soldiers died for no apparent reason, after having eaten small amounts of meat paste with a high fat content. 37 , 38 Anna Reid likewise describes sudden death from refeeding in her account of the siege of Leningrad. 39 In the comprehensive nine-volume work on the Nazi camp system, Der Ort des Terror [The Place of Terror], there was no consensus regarding the number of deaths due to refeeding.…”

Section: The Liberation and Discovery Of A Refeeding Problemmentioning

confidence: 99%

“…However, mineral metabolism and vitamin imbalances were noted, both of which are recognized elements of refeeding syndrome. 37 , 49 Several of the observations in the WW2 studies included hypophosphatemia, hypokalemia, hypomagnesemia, hyponatremia, hypocalcemia, and certain vitamin deficiencies (see Table 1 ).…”

Section: Overview Of Recorded Deaths Of Survivorsmentioning

confidence: 99%

“…In refeeding syndrome, these imbalances can be corrected within 4–5 days with the appropriate treatment; however, treatment must be administered quickly, in conjunction with appropriate measures to stabilize the cardiovascular system. 49 Failure to do so leads to cardiac decompensation, cardiac arrest, and death 37 , 50 —precisely the causes of death that puzzled Dr Dvorjetsky. 31 , 32…”

Section: Overview Of Recorded Deaths Of Survivorsmentioning

confidence: 99%

“…If so, then the tachycardia might have been an early sign of refeeding syndrome, indicative of fluid overload and cardiac failure. 37 …”

Section: Overview Of Recorded Deaths Of Survivorsmentioning

confidence: 99%

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One Page in the History of Starvation and Refeeding

Hemstreet,

Weisz

2024

Rambam Maimonides Med J

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There is a long history of starvation, including reports dated back to antiquity. Despite exceptional scientific developments, starvation still exists today. The medical aspects of starvation were well established in the twentieth century, particularly following studies related to the 1943–1944 Bengal famine in India and starved prisoners of war and survivors of World War 2. The refeeding of the starved victims provided disappointing results. Nevertheless, those studies eventually led to the development of a new branch of research in medicine and to the definition of what is now known as refeeding syndrome. This paper briefly reviews the history and groundwork that led to today’s understanding of starvation and refeeding, with a particular emphasis on the observations from studies on starved Holocaust survivors and prisoners of war after World War 2. The relevance of these studies for modern times is briefly discussed.

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Section: Heart Failurementioning

confidence: 98%

Section: The Liberation and Discovery Of A Refeeding Problemmentioning

confidence: 99%

Section: Overview Of Recorded Deaths Of Survivorsmentioning

confidence: 99%

Section: Overview Of Recorded Deaths Of Survivorsmentioning

confidence: 99%

“…If so, then the tachycardia might have been an early sign of refeeding syndrome, indicative of fluid overload and cardiac failure. 37 …”

Section: Overview Of Recorded Deaths Of Survivorsmentioning

confidence: 99%

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One Page in the History of Starvation and Refeeding

Hemstreet,

Weisz

2024

Rambam Maimonides Med J

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Refeeding Syndrome In Schizophrenia Case Report

DORDOYE,

Fiagbe,

Dziwornu

et al. 2023

gcps

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Background Recent studies have shown growing concern for refeeding syndrome (RFS) among patients suffering from other medical conditions, although the exact incidence in this population is unknown. RFS occurs with the rapid reintroduction of calories to severely malnourished patients. It becomes critical for clinicians to have a high incidence of suspicion for prompt diagnosis and appropriate management to keep them alive if the malnutrition does not take their lives. Case presentation We report a case of a 53-year-old man with an 8-year history of schizophrenia and a 3-month history of poor feeding. He was admitted on account of refusal to feed or drink for two weeks prior to presentation. As a result, he was severely malnourished, and we started refeeding while dealing with his psychotic symptoms. He gained about 2kg within a week of admission, but that was fraught with metabolic derangements, which included, but were not limited to, hypophosphatemia, hypomagnesaemia, and hypocalcaemia. We revised his diagnosis to RFS in schizophrenia and managed it as such. Conclusion Diagnosis of RFS is based on a constellation of electrolyte deficiencies and clinical presentation as there are no agreed biomarkers. Unfortunately, one of the cardinal electrolyte deficiencies, hypophosphatemia, does not have readily available formulations for its correction, and this can lead to neurological, cardiovascular, and other complications, including sudden death. Delay in diagnosis worsens the prognosis, and the intuitive desire to feed a starved patient zealously leads them to death.

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Etiology and Complications of Refeeding Syndrome in the ICU

Cited by 2 publications

References 49 publications

One Page in the History of Starvation and Refeeding

One Page in the History of Starvation and Refeeding

Refeeding Syndrome In Schizophrenia Case Report

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