Etiology and Pathogenesis of Burn Anemia. The Role of the Blood Transfusion in the Treatment of Patients with Burns

Спиридонова, Т. Г.; Жиркова, Е. А.

doi:10.23934/2223-9022-2018-7-3-244-252

Cited by 6 publications

(1 citation statement)

References 70 publications

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“…Триггерный показатель уровня гемоглобина у тяжелообожженных больных для определения показаний к проведению гемотрансфузий эритроцитсодержащих компонентов составляет 90 г/л и менее. Соблюдение подобной тактики будет способствовать проведению адекватного лечения, своевременного оперативного вмешательства и профилактике осложнений [36].…”

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Modern aspects of the monitoring of a burn wound readiness for autodermoplasty

Zurnadzh'yants,

Kchibekov,

Ragimov

et al. 2024

jour

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The leading principle of burned patients’ treatment is to perform free autodermoplasty with split autodermografts. The main criterion for a successful plastic surgery is the percentage of engraftment of skin grafts. The issues of readiness of burn wounds for such surgical interventions continue to be studied and remain open at the present time. The degree of readiness of burn wounds for skin grafting is known to depend on many factors, among which the state of the microbial flora and the level of bacterial contamination of the wound surface play an important role as one of the main criteria for maintaining inflammation in the wound. The method of cytological examination of prints from burn wounds has found wide application, which is associated with the peculiarities of pathomorphological processes in burn wounds. Great importance is attached to studying the state of microcirculation in the wound using laser Doppler flowmetry in order to determine the perfusion and reparative ability of granulation tissue of a burn wound. However, in addition to local criteria, general condition of the body and the state of its immune system in particular should be taken into account. A great number of research works is devoted to the study of immune reactions in response to burn injury. The results of these studies also make it possible to identify certain criteria for predicting the success or chance of unsatisfactory outcomes of autodermoplasty. The levels of hemoglobin and total protein allowing to expect successful surgical treatment have been determined. In spite of the wide range of methods to determe the readiness of a wound for autodermoplasty, many of them are imperfect and nonspecific. The development of complications in the form of lysis or rejection of skin grafts, the maintenance of inflammatory processes, the development of a shortage of donor resources, mortality and the likelihood of developing severe cicatricial deformities in long-term results depend on the quality and timing of surgical treatment. Therefore, the problem of uniform criteria identification for the readiness of a burn wound surface for plastic surgery remains relevant for combustiologists and surgeons.

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Modern aspects of the monitoring of a burn wound readiness for autodermoplasty

Zurnadzh'yants,

Kchibekov,

Ragimov

et al. 2024

jour

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Гиповолемический Шок У Взрослых. Клинические Рекомендации Общероссийской Общественной Организации «Федерация Анестезиологов И Реаниматологов»

Заболотских,

Григорьев,

Афончиков

et al. 2024

Annals of Critical Care

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The article presents the main provisions of clinical guidelines for the diagnosis and treatment of hypovolemic shock in adults, approved by the All-Russian public organization "Federation of Anesthesiologists and Resuscitators" in 2024. The relevance of the problem is associated with a significant prevalence and high mortality rates in hypovolemic shock. The recommendations include issues of etiology, pathogenesis, clinical picture, methods of laboratory and instrumental diagnostics of hypovolemic shock. The features of intensive care for hypovolemic shock are presented, including approaches to the administration of vasopressor and inotropic drugs, recommendations for the choice of infusion and adjuvant therapy, including the correction of coagulopathy in hemorrhagic shock. The issues of resuscitation damage control strategy are discussed. The criteria for the quality of medical care for adult patients with hypovolemic shock and algorithms for the doctor's actions in the diagnosis and intensive care of patients with hypovolemic shock are presented.

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Comparative evaluation of the informative value of methods for determining the volume of intraoperative blood loss in the surgical treatment of burn victims

Zinoviev

Vagner

Chukharev

2021

VESTNIK KHIRURGII IMENI I.I.GREKOVA

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The OBJECTIVE was to evaluate the informative value of various methods for determining the volume of blood loss during early surgical excision with simultaneous skin grafting with split grafts in patients with full thickness burns.MATERIAL AND METHODS. Our study included 10 patients with burns more than 20 % TBSA. In these patients, from the 2nd to the 5th day after the burn, fascial surgical excision with simultaneous skin grafting with perforated split grafts was performed. To assess the volume of operative blood loss, we used visual, empirical (B. S. Vikhriev; 1986, I. V. Chmyrev; 2011, T. A. Housinger; 1993, T. Janezic; 1997) and calculated (J. B. Gross; 1983, P. G. Budny; 1993, G. D. Warden; 1982) methods. The obtained data were processed by the generally accepted methods of nonparametric statistics.RESULTS. The minimum volume of blood loss was ascertained by visual assessment. We observed the maximum losses in the same patients when using calculated methods. In 5 out of 10 patients, the difference between the minimum and maximum results obtained using different methods exceeded 1000 %.CONCLUSION. Most of the methods used in burn surgery for determining the volume of surgical blood loss are insufficiently representative. To determine the optimal tactics for surgical treatment of patients with severe burns, it is necessary to create formulas for assessing the volume of blood loss, which will take into account laboratory parameters, features of surgical treatment, hydrobalance indicators, anthropometric data and other variables with high predictive value.

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Etiology and Pathogenesis of Burn Anemia. The Role of the Blood Transfusion in the Treatment of Patients with Burns

Cited by 6 publications

References 70 publications

Modern aspects of the monitoring of a burn wound readiness for autodermoplasty

Modern aspects of the monitoring of a burn wound readiness for autodermoplasty

Гиповолемический Шок У Взрослых. Клинические Рекомендации Общероссийской Общественной Организации «Федерация Анестезиологов И Реаниматологов»

Comparative evaluation of the informative value of methods for determining the volume of intraoperative blood loss in the surgical treatment of burn victims

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