Etiology, Diagnosis, and Management of Vaginitis

Mashburn, Jane

doi:10.1016/j.jmwh.2006.07.005

Cited by 50 publications

(34 citation statements)

References 40 publications

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“…The addition of potassium hydroxide to the wet mount slide will remove debris that may obscure the hyphae, and assists in making an accurate diagnosis. 13 In present study, VVC was diagnosed on the basis of clinical symptoms of vaginitis and direct microscopic examination. Trichomoniasis was diagnosed by visualisation of motile trichomonads in the wet mount smear, immediately after sampling.…”

Section: Methodsmentioning

confidence: 95%

Prevalence of Bacterial Vaginosis and Impact of Genital Hygiene Practices in Non-Pregnant Women in Zanjan, Iran

Amini¹,

Baghchesaraie²,

Zohre³

2009

OMJ

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Section: Methodsmentioning

confidence: 95%

Prevalence of Bacterial Vaginosis and Impact of Genital Hygiene Practices in Non-Pregnant Women in Zanjan, Iran

Amini¹,

Baghchesaraie²,

Zohre³

2009

OMJ

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“…Among the urogenital infections, BV, VVC and urinary tract infections, together, affect about one billion women worldwide each year. It is estimated that about 75 % of women will have at least one episode of lower genital tract infection in their life and that about half of them will present new occurrences (ACOG, 2006;Mashburn, 2006). Some of the strategies used to manage vaginal tract infections are frequently ineffective in solving the problem.…”

Section: Introductionmentioning

confidence: 99%

Selection of Lactobacillus strains as potential probiotics for vaginitis treatment

et al. 2016

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Jos e de las Lajas Mayabeque, CubaLactobacilli are the dominant bacteria of the vaginal tract of healthy women, and imbalance of the local microbiota can predispose women to acquire infections, such as bacterial vaginosis (BV) and vulvovaginal candidiasis (VVC). Although antimicrobial therapy is generally effective, there is still a high incidence of recurrence and increase of microbial resistance due to the repetitive use of antimicrobials. Thus, it has been suggested that administration of probiotics incorporating selected Lactobacillus strains may be an effective strategy for preventing vaginal infections. Accordingly, the in vitro probiotic potential of 23 lactobacilli isolated from the vaginal ecosystem of healthy women from Cuba was evaluated for use in BV and VVC treatments. Eight strains were selected based on their antagonist potential against Gardnerella vaginalis, Candida albicansor both. In vitro assays revealed that all these strains reduced the pathogen counts in co-incubation, showed excellent adhesive properties (biofilm formation and auto-aggregation), were able to co-aggregate with G. vaginalis and C. albicans, yielded high amounts of hydrogen peroxide and lactic acid and demonstrated high adhesion rates to epithelial HeLa cells. Interference tests within HeLa cells showed that all strains were able to reduce the adherence of pathogens by exclusion or displacement. Lactobacilli were able to inhibit HeLa cell apoptosis caused by pathogens when the cells were incubated with the probiotics prior to challenge. These results suggest that these strains have a promising probiotic potential and can be used for prevention or treatment of BV and VVC.

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“…Как уже отмечалось, длительное антибактериальное лечение хронических вульвовагинитов изменяет эндогенную микроф-лору, обусловливая увеличение числа штаммов, устойчивых к действию антибактериальных препаратов. Именно поэто-му большинство исследователей отводят главную роль ком-плексному лечению, включающему в себя общую и местную терапию, направленную на подавление и ликвидацию пато-генных возбудителей, дезинтоксикацию и коррекцию наруше-ний гемостаза, что способствует повышению защитных спо-собностей организма [27][28][29][30].…”

Section: подходы к лечениюunclassified

Local therapy as a modern trend in the treatment of vaginal infections

Потапов

2016

Reproductive Endocrinology

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ВВЕДЕНИЕВоспалительные заболевания влагалища (ва-гиниты) продолжают оставаться актуальной проблемой современной гинекологии, посколь-ку они распространены среди женщин всех воз-растов. Так, у молодых женщин основными при-чинами, способствующими развитию вагинитов, как правило, являются инфекционные заболева-ния, эндокринная патология, снижение функции яичников, воздействие местных повреждающих факторов. В свою очередь в пожилом и старче-ском возрасте на развитие неспецифических вагинитов влияет утрата одного из важных фак-торов защиты слизистой оболочки влагалища, а именно возможности образования молочной кислоты из гликогена [1,2,3].Воспалительные заболевания влагалища ухудшают качество жизни женщин, способ-ствуют развитию воспалительного процесса матки и ее придатков, приводят к инфекци-онным осложнениям после хирургического вмешательства на органах малого таза, зна-чительно снижают репродуктивный потенци-ал женщин, а также влияют на возникновение восходящей инфекции мочевыводящих пу-тей, обусловливая развитие циститов и пие-лонефритов [4,5,6].

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Etiology, Diagnosis, and Management of Vaginitis

Cited by 50 publications

References 40 publications

Prevalence of Bacterial Vaginosis and Impact of Genital Hygiene Practices in Non-Pregnant Women in Zanjan, Iran

Prevalence of Bacterial Vaginosis and Impact of Genital Hygiene Practices in Non-Pregnant Women in Zanjan, Iran

Selection of Lactobacillus strains as potential probiotics for vaginitis treatment

Local therapy as a modern trend in the treatment of vaginal infections

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