Etiology of Chylothorax in 203 Patients

Doerr, Clinton H.; Allen, Mark S.; Nichols, Francis C.; Ryu, Jay H.

doi:10.4065/80.7.867

Cited by 327 publications

(301 citation statements)

References 34 publications

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“…In addition, the overall number of patients in the study was modest because chylothorax is an uncommon form of pleural effusion. As previously observed, 12 the high number of postsurgical chylothorax cases may directly reflect the larger number of cardiothoracic surgical procedures performed at our institution, which may limit the generalizability of our results.…”

Section: Discussionmentioning

confidence: 68%

Pleural Fluid Characteristics of Chylothorax

Maldonado

Hawkins

Daniels

et al. 2009

Mayo Clinic Proceedings

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220

157

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OBJECTIVE:To determine the biochemical parameters of chylous pleural fluids and better inform current clinical practice in the diagnosis of chylothorax. PATIENTS AND METHODS:We retrospectively reviewed 74 patients with chylothorax (defined by the presence of chylomicrons) who underwent evaluation during a 10-year period from January 1, 1997, through December 31, 2006. The biochemical parameters and appearance of the fluid assessed during diagnostic evaluation were analyzed. RESULTS:The study consisted of 37 men (50%) and 37 women (50%), with a median age of 61.5 years (range, 20-93 years). Chylothorax was caused by surgical procedures in 51%. The chylous pleural fluid appeared milky in only 44%. Pleural effusion was exudative in 64 patients (86%) and transudative in 10 patients (14%). However, pleural fluid protein and lactate dehydrogenase levels varied widely. Transudative chylothorax was present in all 4 patients with cirrhosis but was also seen with other causes. The mean ± SD triglyceride level was 728±797 mg/dL, and the mean ± SD cholesterol value was 66±30 mg/dL. The pleural fluid triglyceride value was less than 110 mg/dL in 10 patients (14%) with chylothorax, 2 of whom had a triglyceride value lower than 50 mg/dL.

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Section: Discussionmentioning

confidence: 68%

Pleural Fluid Characteristics of Chylothorax

Maldonado

Hawkins

Daniels

et al. 2009

Mayo Clinic Proceedings

Self Cite

220

157

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show abstract

“…Apart from trauma and malignancies (especially lymphoma), chylothorax and chyloabdomen may develop in filariasis, lymphangioleiomyomatosis, amyloidosis, cirrhosis, thrombosis in the jugulo-subclavian region, pericarditis, nephrotic syndrome, sarcoidosis, tuberculosis and in the post-radiotherapy stage in malignancies [5]. In a series of 203 patients reported by Doerr et al, surgery or trauma was present in 101 patients, lymphoma and lymphatic disorders were detected in 89 patients, and idiopathic chylopathology was determined in 13 patients [7].…”

Section: Discussionmentioning

confidence: 99%

Nonspecific Infectious Bilateral Chylothorax and Cyhloabdomen with Symptoms of Acute Abdomen

Sayır

Çobanoğlu

Şehitoğulları

2011

EAJM

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Co-existence of chylothorax and chyloabdomen is a rare clinical entity. Apart from surgery and extra-surgical trauma, malignancies, liver cirrhosis, nephrotic syndrome, thrombosis in the superior vena cava and acute pancreatitis play roles in the etiology. The case presented in this article was a 35-year-old woman, and the chronic infectious pathology in the cytology, plus the other supportive nonspecific infection parameters prompted us in establishing this diagnosis. Obstruction in the abdominal lymphatics leads to chylous ascites and chylothorax develops in due course. Similar to our case, the clinical entities of chylothorax and chyloabdomen of nonspecific infectious origin may co-exist in the same patient. Key Words: Chylothorax, Chyloabdomen, Management ÖzetŞilotoraks ve şiloabdomen birlikteliği, nadir bir klinik antitedir. Cerrahi ve cerrahi dışı travmadan başka, malignensiler, karaciğer sirozu, nefrotik sendrom, vena cava superior trombozu ve akut pankreatit gibi nedenler etyolojide rol oynar. Sunulan olgu, 35 yaşında, bayan hasta. Etyolojide tesbit edilen infeksiyöz patolojiyi sitoloji ve diğer destekleyici parametreler belirledi. Abdominal lenfatiklerin tıkanması, şilöz asit ve şilotoraks oluşumuna yol açmaktadır. Olgumuzda olduğu gibi, şilotoraks ve şiloabdomenin birlikte görülmesi, nonspesifik-infeksiyöz nedenli olarak da görülebilmektedir.

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“…Approximately 5% to 10% of chylothoraces have no immediate causative factor at the time of presentation and may therefore be regarded as idiopathic [13] . Pleurisy associated with tuberculosis, pneumonia or lupus may obstruct intercostal lymphatic channels.…”

Section: Discussionmentioning

confidence: 99%

Bilateral chylothorax complicating bibasilar pneumonia: A case report

Onen¹,

Ndosi²,

Sibanda³

et al. 2015

CRIM

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A 24-year-old previously healthy, HIV-negative lady with acute respiratory symptoms for one week, presented with bilateral chylous pleural effusions and bibasilar pneumonia. She responded rapidly to antimicrobial therapy and bilateral tube thoracostomies. Analysis of a sample of right pleural fluid confirmed exudative chylous effusion. No organisms were identified on fluid microscopy or culture. The left pleural fluid was macroscopically chylous. She had no features of tuberculosis. Bilateral chylothorax complicating bibasilar pneumonia is considerably rare.

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Etiology of Chylothorax in 203 Patients

Cited by 327 publications

References 34 publications

Pleural Fluid Characteristics of Chylothorax

Pleural Fluid Characteristics of Chylothorax

Nonspecific Infectious Bilateral Chylothorax and Cyhloabdomen with Symptoms of Acute Abdomen

Bilateral chylothorax complicating bibasilar pneumonia: A case report

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