Etiology of hospital infections registered in University Hospital No. 2 in Bydgoszcz in 2015–2017

Kuziemski, Arkadiusz; Frankowska, K; Gonia, Ewa

doi:10.31350/zakazenia/2018/5/z2018040

Medicine

2018

DOI: 10.31350/zakazenia/2018/5/z2018040

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Etiology of hospital infections registered in University Hospital No. 2 in Bydgoszcz in 2015–2017

Arkadiusz Kuziemski¹,

K Frankowska²,

Ewa Gonia³

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2023

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The Occurrence of Methicillin-Resistant Staphylococcus Aureus (MRSA) Around the World and Antibiotic Therapy for Selected Infections Caused By MRSA

Wierzchowska

2023

Postępy Mikrobiologii - Advancements of Microbiology

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Staphylococcus aureus is a Gram-positive bacterium, which can cause serious bacterial infections in humans. It constitutes an important etiological factor of many diseases, for instance, soft tissue and skin infections (including skin boils and abscesses), as well as life-threatening necrotizing pneumonia or toxic shock syndrome. It is estimated that about 25–30% of people are carriers of S. aureus mainly in the anterior nostrils. A smaller percentage of people are carriers of methicillin-resistant S. aureus (MRSA). In accordance with its definition, methicillin-resistant S. aureus is resistant to almost all β-lactam antibiotics. This phenomenon is mainly caused by the presence of penicillin-binding protein in the cell wall – PBP2a, which is the product of the mecA gene, which is part of the complex called SCCmec (staphylococcal cassette chromosome mec). Methicillin-resistant S. aureus (MRSA) results in endemic in hospitals around the world and are one of the leading causes of morbidity and mortality in society. Infections initiated by hospital strains of MRSA (health care-associated MRSA, HA-MRSA) concern mainly immunocompromised patients after surgery. In addition, there are populations of acommunity-associated MRSA (CA-MRSA) strains and populations of livestock-associated MRSA (LA-MRSA) strains. The treatment of infections with MRSA etiology, after exhausting the possibilities of standard antibiotic therapy with the use of i.e. vancomycin, is based on treatment with new-generation antibiotics, such as dalbavacin.

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The Occurrence of Methicillin-Resistant Staphylococcus Aureus (MRSA) Around the World and Antibiotic Therapy for Selected Infections Caused By MRSA

Wierzchowska

2023

Postępy Mikrobiologii - Advancements of Microbiology

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show abstract

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Etiology of hospital infections registered in University Hospital No. 2 in Bydgoszcz in 2015–2017

Cited by 1 publication

References 0 publications

The Occurrence of Methicillin-Resistant Staphylococcus Aureus (MRSA) Around the World and Antibiotic Therapy for Selected Infections Caused By MRSA

The Occurrence of Methicillin-Resistant Staphylococcus Aureus (MRSA) Around the World and Antibiotic Therapy for Selected Infections Caused By MRSA

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