Etiopathogenetic factors of infective endocarditis in patients undergoing mitral valve surgery

Abstract

Objective. To determine the etiopathogenetic risk factors for the development of infective endocarditis, taking into account demographic and gender characteristics in patients undergoing mitral valve surgery. Materials and methods. The study included 107 patients who underwent mitral valve surgery. There were 74 men and 33 women. The age of the patients ranged from 20 to 76 years, with a mean age of (50.6 ± 4.8) years. All patients had a history of infective endocarditis with subsequent mitral valve disease. All patients underwent mitral valve repair/prosthetics at the Amosov National Institute of Cardiovascular Surgery of the National Academy of Medical Sciences of Ukraine. Data from the primary medical records (medical histories, primary medical records, physical, clinical, laboratory and instrumental examinations) were used as the basis for the analysis. Results. Depending on the surgical treatment performed, patients were divided into two groups: experimental – 67 patients who underwent organ–preserving surgery (mitral valve repair), and control – 40 patients who underwent mitral valve prosthetics. The peculiarities of age and gender distribution of patients with mitral valve disease in the setting of infective endocarditis were studied. The frequency of etiopathogenetic risk factors for the development of infective endocarditis, taking into account the sex of patients in both study groups, was determined. Conclusions. Determination of etiopathogenetic risk factors for the development of infective endocarditis is extremely important, as it allows to plan surgical treatment and rehabilitation period taking into account all anamnestic features of the patient.