1955
DOI: 10.1016/0006-3002(55)90234-1
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Étude de l'action des membranes du bactériophage T2 sur Escherichia Coli

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Cited by 41 publications
(41 citation statements)
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“…Without presenting the detailed evidence, for it is to be discussed in the next paper, there is evidence for heterogeneity in the ghost preparations. Thus, it has been observed in this and other (11,14) laboratories that not all the ghosts can "kill" the host cells. With such heterogeneity in the ghost preparations, basing the unit of ghost action on the number would appear to be meaningless.…”
Section: Proof Of Lysis Of Cells Bymentioning
confidence: 63%
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“…Without presenting the detailed evidence, for it is to be discussed in the next paper, there is evidence for heterogeneity in the ghost preparations. Thus, it has been observed in this and other (11,14) laboratories that not all the ghosts can "kill" the host cells. With such heterogeneity in the ghost preparations, basing the unit of ghost action on the number would appear to be meaningless.…”
Section: Proof Of Lysis Of Cells Bymentioning
confidence: 63%
“…These results are comparable to those reported by Hershey (6,12) and more recently by French and Siminovitch (14). Using the electron microscope Bonifas and Kellenberger (11) reported that nearly 99 per cent of the ghosts were removed by adsorption. This discrepancy in findings suggests that non-sedimentable ghost protein may be formed following the union of ghosts and cells.…”
Section: Proof Of Lysis Of Cells Bymentioning
confidence: 99%
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“…After T4 or T2 infection a typical morphological modification of the bacterial nucleus takes place (6,20,30) which is now called nuclear disruption (40). Snustad et al (40) have shown that nuclear disruption is independent of the chemical breakdown of host DNA; the 2 phenomena are controlled by different genes (39).…”
Section: Early Morphological Events After Infection With the G Mutantmentioning
confidence: 99%
“…The results showing that 15 to 20 per cent of the label is not adsorbed to host cells with radioactive S35-1abelled phage and ghosts, confirm the earlier experiments of Hershey (5,6) and the recent ones of French and Siminovitch (7). However, using an electron microscope Bonifas and Keilenherger (8) have examined a comparable supernatant fluid following centrifugation and report that no ghosts could be found though as little as 0.1 per cent of the initial number could be detected if present. This means that some interpretation other than the non-adsorption of some ghosts must be found.…”
Section: Host Range Specif~ity Adsorpt4on Of S S5 Tg Phage and Ghostmentioning
confidence: 99%