Étude de prévalence des effets indésirables liés à l’utilisation des plantes médicinales par les patients de l’Institut National d’Oncologie, Rabat

Chebat, Abderrahim; Skalli, Souad; Errihani, Hassan; Boulaamane, L.; Mokrim, Maha; Mahfoud, Tarik; Soulaymani, R.; Kahouadji, A.

doi:10.1007/s10298-013-0828-4

Cited by 38 publications

(17 citation statements)

References 25 publications

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“…We have to acknowledge that the use values that we report are lower than reported in other studies for other disease [31]. However, these studies examine other diseases, so our results could possibly be related to the severity of the disease and the sensitization compared to the adverse effects following the use plants [6].…”

Section: Ethnobotanical Indicescontrasting

confidence: 57%

“…Consequently, related to this rich diversity, Morocco has been shown to be a very important exporter of medicinal plants [5]. Local populations and traditional healers in the region of Meknes-Tafilalet use those medicinal plants to prevent and/or treat many diseases, including cancer [6]. According to WHO in 2014, 11% of all death in Morocco was due to cancer, which is remarkably lower than the worldwide incidence (~17%).…”

Section: Introductionmentioning

confidence: 99%

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Complimentary Herbal Treatments Used in Meknes-Tafilalet Region (Morocco) to Manage Cancer

Fakir¹,

Bito²,

Zaîd³

et al. 2019

AJPS

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Background. In Morocco, the use of folk medicine and phytotherapy is very common to treat several diseases including cancer. The aim of our study was to perform an ethnobotanical investigation of the plants used in traditional medicine to treat cancer in the region of Meknès-Tafilalet. Methods. An ethnobotanical survey has been conducted in Meknès-Tafilalet region (Meknès, Errachidia, Moulay Idriss, Khenifra, Ifrane and Azrou). Information was gathered from traditional healers, herbalists, patients and users of medicinal plants using semi-structures questionnaires. Results. Our study demonstrates that the practice of phytotherapy for the treatment of diseases and cancer in particular is important since 68.5% of the informants indicated using medicinal plants. In addition, our study reports that 35 different plants, belonging to 23 botanical families, are used in the Meknes-Tafilalet region. Of those, Lamiaceae, Asteraceae, Liliaceae and Fabaceae are the most used families. In addition, we show that Aristolochia longa is the plant mainly used to treat cancer specifically. Our data indicate that leaves and seeds (respectively 36.9% and 28.6%) are the parts of the plants mainly used, largely processed in powder (76.9%). Our data indicate that despite unprecise data on the posology, adverse effects are seen only in 15% of the cases. Conclusion. Our study is an essential documentation on traditional use of medicinal plants in Meknes-Tafilalet region that will contribute to the preservation of the ancestral knowledge and will promote protection of biodiversity of this region.

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Section: Ethnobotanical Indicescontrasting

confidence: 57%

Section: Introductionmentioning

confidence: 99%

Complimentary Herbal Treatments Used in Meknes-Tafilalet Region (Morocco) to Manage Cancer

Fakir¹,

Bito²,

Zaîd³

et al. 2019

AJPS

View full text Add to dashboard Cite

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“…In view of the difficulties in controlling the market of traditional medicine, a system of phytovigilance is needed. This system of information and reporting of adverse events allows a better evaluation of adverse reactions among users of medicinal species [22] .…”

Section: Resultsmentioning

confidence: 99%

Ethnopharmacological Study of Herbal Medicines used to treat Cancer in Morocco

Samouh¹,

Lemrani²,

Hajar³

et al. 2019

J Phytopharmacol

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Since the dawn of time, humans use plants to relieve their ills and diseases; cancer is no exception to this rule. Traditional medicine is an important part of health care but often underestimated. Aim of the study: The purpose of this investigation was to determine the prevalence of Medicinal Plants use in oncology, establish the list of plants used to treat cancer and evaluate this practice risks on the health of patients. Methods: Cross-sectional study based on a questionnaire on the use of medicinal plants by patients with cancer in unit of oncology of the university teaching hospital IBN Rochd of Casablanca, Morocco. A questionnaire was distributed to 1325 patients in face to face interviews. Results: Our study involved 1325 patients. Women made up 75% of the population, compared with 25% of men, with a ratio of 0.33. The found prevalence of plants use in our population of patients was high at 38%. 63 herbal medicine species under 38 families have been identified. The most commonly used species were essentially the Marrubium vulgare L followed by the Aristolochia longa, the Berberis vulgaris. Seeds, leaves and fruits are the most commonly used plant parts of plants to treat cancer. Decoction and infusion were the most commonly used method of preparation. The most common type of cancer treated with traditional medicines was breast cancer followed by uterus, colon and leukaemia. Conclusion: This survey provides an updated list of medicinal plants used by the entire Moroccan population. To assess the efficacy and the safety of reported herbs, Clinical and randomized trials are needed hereafter.

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“…The most predominant botanical families used as anticancer agents were Lamiaceae (13 species), Apiaceae (9 species), Compositae (8 species), and Fabaceae (6 species; Figure 1 ). Two surveys conducted at the National Institute of Oncology in Rabat (Morocco) showed that the most used plants by the patients were Nigella sativa L. (Ranunculaceae), Trigonella foenum-graecum L. (Fabaceae), Aristolochia longa L. (Aristolochiaceae), Marrubium vulgare L. (Lamiaceae), and Cassia absus L. (Fabaceae) (Kabbaj et al, 2012 ; Chebat et al, 2014 ). Recently, a review was conducted on the anticancer potential of plants used in the Arabian and Islamic world (Ahmad et al, 2016 ) which included N. sativa .…”

Section: Ethnobotanical Studiesmentioning

confidence: 99%

North African Medicinal Plants Traditionally Used in Cancer Therapy

et al. 2017

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Background: Cancer is a major cause of mortality worldwide with increasing numbers by the years. In North Africa, the number of cancer patients is alarming. Also shocking is that a huge number of cancer patients only have access to traditional medicines due to several factors, e.g., economic difficulties. In fact, medicinal plants are widely used for the treatment of several pathologies, including cancer. Truthfully, herbalists and botanists in North African countries prescribe several plants for cancer treatment. Despite the popularity and the potential of medicinal plants for the treatment of cancer, scientific evidence on their anticancer effects are still scarce for most of the described plants.Objective: Bearing in mind the lack of comprehensive and systematic studies, the aim of this review is to give an overview of studies, namely ethnobotanical surveys and experimental evidence of anticancer effects regarding medicinal plants used in North Africa for cancer therapy.Method: The research was conducted on several popular search engines including PubMed, Science Direct, Scopus and Web of Science. The research focused primarily on English written papers published between the years 2000 and 2016.Results: This review on plants traditionally used by herbalists in North Africa highlights that Morocco and Algeria are the countries with most surveys on the use of medicinal plants in folk medicine. Among the plethora of plants used, Nigella sativa and Trigonella foenum-graecum are the most referred ones by herbalists for the treatment of cancer. Moreover, a plethora of scientific evidence qualifies them as candidates for further drug development. Furthermore, we report on the underlying cellular and molecular mechanisms.Conclusion: Overall, this review highlights the therapeutic potential of some medicinal plants as anticancer agents. The North African flora offers a rich source of medicinal plants for a wide array of diseases, including cancer. The elucidation of their modes of action represents an indispensable condition for the rational development of new drugs for cancer treatment. Furthermore, testing the anticancer activity in vivo and in clinical trials are warranted to explore the full therapeutic potential of North African plants for cancer therapy.

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Étude de prévalence des effets indésirables liés à l’utilisation des plantes médicinales par les patients de l’Institut National d’Oncologie, Rabat

Cited by 38 publications

References 25 publications

Complimentary Herbal Treatments Used in Meknes-Tafilalet Region (Morocco) to Manage Cancer

Complimentary Herbal Treatments Used in Meknes-Tafilalet Region (Morocco) to Manage Cancer

Ethnopharmacological Study of Herbal Medicines used to treat Cancer in Morocco

North African Medicinal Plants Traditionally Used in Cancer Therapy

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