Recent years have seen significant advances in the field of anatomical pedagogy. Among these major advances, the introduction of clinical reasoning in the early years of the medical curriculum has modified and modernized the approach to teaching anatomy. At the Faculty of Medicine of the Gaston Berger University of Saint-Louis, conventional high-school teaching has been enriched by this new teaching method.Clinical reasoning is the foundation of medical practice, it brings together processes of thought and decision making that allow the clinician to take the most appropriate actions in a specific context of problem solving. However, learning and teaching clinical reasoning are particularly demanding, especially in a discipline such as anatomy, and during first years of the medical curriculum. Apart from the basic knowledge of anatomy, clinical reasoning also requires cognitive abilities from students. Despite these difficulties, the teaching of anatomy can be an interesting basis for learning and practicing clinical reasoning.Our experience shows that even at the beginning of their curriculum, medical students may be confronted with clinical situations. In anatomy, this scenario improves the motivation and understanding of students. Moreover, it represents an exercise in which students feel valued because they are playing their future role in the care team.