Étude sérologique de la toxoplasmose chez les femmes enceintes de Franceville, Gabon

Mickoto, Bertrand Mpiga; Akué, Jean Paul; Bisvigou, Ulrick; Tsonga, S. Mayi; Nkoghe, Dieudonné

doi:10.1007/s13149-009-0031-6

Cited by 9 publications

(10 citation statements)

References 4 publications

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“…The seronegative T. gondii prevalence (42,75%) found here was consistent with previous data (56%) from Franceville in 2007 [53]. Our results also seems to show a decline of seropositivity against T. gondii when compared to similar studies from 1995 and 1997 [54].…”

Section: Discussionsupporting

confidence: 92%

Non-malarial infectious diseases of antenatal care in pregnant women in Franceville, Gabon

Moukandja

Ngoungou

Lémamy

et al. 2017

BMC Pregnancy Childbirth

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BackgroundIn sub-tropical countries, infectious diseases remain one of the main causes of mortality. Because of their lack of active immunity, pregnant women and their unborn children represent the most susceptible people. In Gabon, data on infectious diseases of pregnant women such as syphilis and rubella are either scarce or very old. Few studies have assessed T. gondii infection during pregnancy in the country. Here, we evaluate seroprevalence of HIV, HTVL-1, syphilis and T. gondii and rubella infection during antenatal care among women living in Franceville, Gabon.MethodsA retrospective study was conducted on data collected from May 2007 to July 2010. After signing an informed written consent form, all pregnant women consulting in two hospitals of Franceville (Gabon) and in offices of maternity and childbirth health centers were included. Demographic and clinical data were collected. Serum samples were collected and analysed using immunological assays relevant for HIV (Genscreen HIV-1 version 2, Bio-Rad®, Marne la Roquette, France).HTLV-1 (Vironostika HTLV-1, Biomérieux®, Marcy l’Etoile, France), T. pallidum (TPHA/VDRL), BIOLABO®SA), rubella virus (Vidas Biomerieux®, Marcy l’Etoile, France) and T. gondii (Vidas Biomerieux®, Marcy l’Etoile, France) diagnoses were performed. Data analysis was done using the Stat view 5.0 software.ResultsA total of 973 pregnant women were assessed. The mean age was 25.84 ± 6.9 years, with a minimum age of 14.0 years and a maximum of 45.0 years. Women from 26 to 45 years old and unemployed women were the most prevalent: 41.93% and 77.18%, respectively. The prevalence of studied infectious diseases were 2.50% for syphilis, 2.88% for HTLV-1, 4.00% for HIV with no significant difference between them (p = 0.1). Seropositivity against rubella was higher (87.56%, n = 852) than seropositivity against T. gondii (57.35%, n = 557), (p < 0.0001). Only 5 (0.51%) co-infection cases were found: 2 co-infected with HIVand T. pallidum, 2 co-infected with HIV and HTLV-1, and one co-infected with T. pallidum and HTLV-1. Sixty-two pregnant women were seronegative against toxoplasmosis and rubella (6.37%).ConclusionHigh levels of seropositivity against T. gondii and the rubella virus were observed. The prevalence of T. pallidum and HTLV-1 were lowest but HIV prevalence in young women was worrying.

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Section: Discussionsupporting

confidence: 92%

Non-malarial infectious diseases of antenatal care in pregnant women in Franceville, Gabon

Moukandja

Ngoungou

Lémamy

et al. 2017

BMC Pregnancy Childbirth

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“…The seroprevalence values observed are higher than the ones reported in countries geographically close to the DRSTP, such as Nigeria, with 32.0% (Ohiolei & Isaac, 2016), Gabon, with 56.0% (Mickoto et al, 2010), and Cameroon, with 70.0% (Njunda et al, 2011). In addition to the climatic variations, there are still sociocultural and dietary differences, which may explain such prevalence variations (Fan et al, 2006;Njunda et al, 2011;Rahimi et al, 2015;Wam et al, 2016).…”

Section: Discussionmentioning

confidence: 57%

Seroepidemiology of Toxoplasma gondii in domestic cattle, sheep, goats and pigs from São Tomé and Príncipe

Pereira

Mata

Neto

et al. 2020

Rev. Bras. Parasitol. Vet.

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Despite the global importance of the zoonotic parasite Toxoplasma gondii, little is known regarding its infection in the Democratic Republic of São Tomé and Príncipe (DRSTP). This is the first report of antibodies to T. gondii in cattle, sheep, goats and pigs from the DRSTP. Antibodies were assessed by the modified agglutination test (MAT), with a cut-off titer of 100 for cattle and 20 for sheep, goats and pigs. The present study revealed an overall seroprevalence of 55.8%; 27.1% in 48 cattle, 68.4% in 98 sheep, 70.1% in 97 goats and 43.7% in 103 pigs. The south geographical area for cattle, the central area for sheep, and adult age and living in the central region for goats were found to be risk factors for seropositivity to T. gondii. These results support the scenario of a considerable presence of sporulated oocysts as well as of infected intermediate hosts in the local environment. Consumption of raw or undercooked meat should be considered as an important potential source of infection for animals and humans in the DRSTP.

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“…As for female donors, 5.66% prevalence of both IgG and IgM was found. This prevalence was much lower than that found in pregnant women in Côte d'Ivoire [ 2 – 4 ], Burkina Faso (31%) [ 24 ], Gabon (56%) [ 25 ], and Morocco (50.6%) [ 26 ]. This difference was probably related to the selection of blood donor before donation, to assess their eligibility to donate before retaining them as donor.…”

Section: Discussionmentioning

confidence: 71%

Immunity Status of Blood Donors RegardingToxoplasma gondiiInfection in a Low-Income District of Abidjan, Côte d’Ivoire, West Africa

Siransy

Dassé

Gonat

et al. 2016

Journal of Immunology Research

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Background. Toxoplasmosis is a widespread cosmopolitan anthropozoonosis, which affects more than a third of the world population. Except the modes of transmission well known, Toxoplasma gondii can be transmitted during transplantation or blood transfusion. The aim of this study is to determine the prevalence of IgG and IgM Toxoplasma gondii and to estimate the potential risk by blood products. Methods. This is a cross-sectional study on the research for Toxoplasma gondii antibodies (IgG and IgM) blood donors performed by ELISA. Results. An overall seroprevalence of Toxoplasma gondii among blood donors recruited was 67.92% (n = 72). Among these, 68 have Toxoplasma gondii IgG (64.15%), 12 Toxoplasma gondii IgM (11.32%), and 4 (3.77%) both. The risk varies between 8 for 100000 and 172 for 100000 donations. Conclusion. The need to strengthen security measures for people multitransfused, immunocompromised, and pregnant women to reduce the transmission of toxoplasmosis is important.

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Étude sérologique de la toxoplasmose chez les femmes enceintes de Franceville, Gabon

Cited by 9 publications

References 4 publications

Non-malarial infectious diseases of antenatal care in pregnant women in Franceville, Gabon

Non-malarial infectious diseases of antenatal care in pregnant women in Franceville, Gabon

Seroepidemiology of Toxoplasma gondii in domestic cattle, sheep, goats and pigs from São Tomé and Príncipe

Immunity Status of Blood Donors RegardingToxoplasma gondiiInfection in a Low-Income District of Abidjan, Côte d’Ivoire, West Africa

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