Etudes des facteurs histo-pronostiques des cancers gastriques opérés au Centre Hospitalo-Universitaire de Fès

Sylla, Moussa; Ossibi, Pierlesky Elion; Soumana, Ismaël Dandakoye; Souiki, Tarik; Toughraï, Imane; Ousadden, Abdelmalek; Mazaz, Khalid; Majdoub, Karim Hassani Ibn

doi:10.11604/pamj-cm.2020.4.54.23112

Cited by 2 publications

(4 citation statements)

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“…This explains why the survival of patients of both sexes and of all ages is affected in an almost similar way. The study conducted by M. Sylla et al [11] , on the histoprognostic factors of gastric cancer, showed on the other hand that an advanced age negatively affected the survival of patients with gastric cancer.…”

Section: Discussionmentioning

confidence: 99%

“…Hepatic, pulmonary or peritoneal invasion is noted. Research on cancer all agree on this subject [4,5,15,21,11,29,30] . Age and sex were not retained in our study as independent factors, significantly associated neither with survival nor with the occurrence of death.…”

Section: Discussionmentioning

confidence: 99%

“…Thus, the most relevant predictors are selected to constitute the prognostic equation. M. Sylla et al [11] , adopted the same procedure to identify and evaluate pre-, intra-and post-operative histo prognostic factors in terms of occurrence of local recurrence, metastasis and overall survival with or without recurrence for patients with gastric cancer. The results showed that at the 5% threshold, the occurrence of metastasis was an unfavorable prognostic factor (OR=27.36), whereas reintervention increased the chances of survival (P=0.007, OR=0.07).…”

Section: Discussionmentioning

confidence: 99%

“…This situation favors a latediagnosis and management and very low survival rates, in the order of 20 to 30%, at 5 years [4,5,21] . Researchers have made extensive use of logistic regression [6] to identify factors predictive of the occurrence of medical events such as confirmation of pathology [7,8] , the appearance of complications such as metastases or tumor recurrence [9,10] , and death [11,12,13] . While the Cox proportional hazard model [14] was applied in the presence of survival data to determine the independent, associated parameters [15,16,10,17,18] .…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Study of prognostic factors in gastric cancer: Application of a cox model and logistic regression

SY¹,

Bousso²,

Correa³

et al. 2022

Int. J. Stat. Appl. Math.

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Introduction: Gastric cancer has a poor prognosis. It is the fifth most common cancer in terms of incidence and the fourth most common cancer in terms of mortality world wide. The aim of our study is to identify the clinical and pathological factors associated with survival and predictive of death. Method: Our study included 262 patients over a 13-year periodfrom 2007 to 2020 at Aristide Le Dantec Hospital in Senegal and Conakry Hospital in Guinea. The survival period was established from one month after treatment to the date of death or last news. We first used the Cox proportional hazard model to identify independent factors associated with survival. Then we applied logistic regression to these factors to develop the prognostic equation. Results:The overall survival at 6 months, 1 year and 5 years after treatment was respectively 74%, 57%, 38%. The probability of occurrence of death after 5 years can be estimated with 93\% accuracy, by: log (π i / (1 -π i )) = -19,983 + 2,119* Métastases + 1,268* Ulcère gastrique + 1,100* Tabac + 37,646* Epigastralgie + 37,563* Cardiopathie + 37,220*Mucineux. Conclusion: Our approach contributes to determine the impact of clinical and pathological factors on the survival of patients and the eventual occurrence of death related to stomach cancer.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%