Eucalyptus brevifolia F. Muell and Eucalyptus stricklandii Maiden leaves extracts: HPLC-DAD, GC-MS analysis and in vitro biological activities, combined with the principal component analysis

Hassine, Dorsaf Ben; Rahmani, Rami; Souchard, Jean‐Pierre; Abderrabba, Manef; Bouajila, Jalloul

doi:10.1016/j.sajb.2022.03.027

Cited by 7 publications

(4 citation statements)

References 36 publications

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“…Eucalyptus leaves extract has been increasingly recognized as a rich source of bioactive molecules for the successful production of different NP [38,45,68]. In this work, the extraction yield was 18.4 (±0.1)% and similar results were obtained by Hassine et al [69].…”

Section: Identification Of Biomolecules In Eucalyptus Leaves Extractsupporting

confidence: 86%

Environmental Remediation Promoted by Silver Nanoparticles Biosynthesized by Eucalyptus Leaves Extract

Rocha¹,

Ferreira-Santos²,

Genisheva³

et al. 2023

Preprint

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Section: Identification Of Biomolecules In Eucalyptus Leaves Extractsupporting

confidence: 86%

Environmental Remediation Promoted by Silver Nanoparticles Biosynthesized by Eucalyptus Leaves Extract

Rocha¹,

Ferreira-Santos²,

Genisheva³

et al. 2023

Preprint

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“…The quantification of each compound was expressed as milligrams per gram (mg/ g) of the respective total extract (Table 2). Moreover, a further supported literature data was used for the compound determination [20–29] …”

Section: Resultsmentioning

confidence: 99%

“…Moreover, a further supported literature data was used for the compound determination. [20][21][22][23][24][25][26][27][28][29] The detected chemical compounds in the organic extracts from the two Limonium. Mill species were given in Table 2 and Figure 2.…”

Section: Hplc Analysis Of Limonium Species Extractsmentioning

confidence: 98%

Comparative Analysis of Organic Extracts Bioactivity from Two Limonium. Mill Species Growing Wild in Tunisian Salty Marshes

Rahmani,

Debouba,

Aydi

et al. 2023

Chemistry & Biodiversity

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Limonium. Mill is a genus of flowering plants belonging to the Plumbaginaceae family. The present study aimed to compare two Limonium species (L. pruinosum Kuntze and L. tunetanum (Barratte & Bonnet) Maire) in terms of their chemical composition and bioactivity. Chemical profiling showed that the methanolic (MeOH) extracts of both species were the most enriched with total phenolic (TP) and total flavonoid (TF) contents. The TFC were higher in L. tunetanum compared to L. pruinosum. HPLC‐DAD analysis showed that distinctly the gallic acid and L‐tyrosine 7‐amido‐4‐methylcoumarin were the main compounds for L. pruinosum and L. tunetanum, respectively. For both Limonium. Mil species, the MeOH extracts displayed the highest antioxidant with IC50 of 7.7 and 8.4 μg/mL for L. pruinosum and L. tunetanum, respectively. The highest anti‐15‐lipoxygnase activity was recorded in the ethyl acetate (IC50=14.2 μg/mL) and Methanol (IC50=15.6 μg/mL) extracts for L. pruinosum. However, for L. tunetanum the best activity was recorded for dichloromethane extract (IC50=10.4 μg/mL). L. pruinosum extracts displayed the highest cytotoxic activity against MCF‐7 and HCT‐116 cell lines compared to L. tunetanum ones. The obtained bioactivity discrepancy between Limonium. Mill species was discussed in relation to the organic extract chemical richness.

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“…Recently, in a study conducted by Ben Hassine and colleagues [21], the petroleum ether extract of E. brevifolia was analyzed using GC-MS. Their research revealed a composition primarily characterized by high levels of eucalyptol and spathulenol, followed by globulol and epiglobulol. However, it is important to note that specific percentages were not provided in their report.…”

Section: Discussionmentioning

confidence: 99%

Chemical Composition, Antibacterial Properties, and Anti-Enzymatic Effects of Eucalyptus Essential Oils Sourced from Tunisia

Khedhri,

Polito,

Caputo

et al. 2023

Molecules

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This study was conducted to examine the chemical composition of the essential oils (EOs) from six Tunisian Eucalyptus species and to evaluate their anti-enzymatic and antibiofilm activities. The EOs were obtained through hydro-distillation of dried leaves and subsequently analyzed using GC/MS. The main class of compounds was constituted by oxygenated monoterpenes, particularly prominent in E. brevifolia (75.7%), E. lehmannii (72.8%), and E. woollsiana (67%). Anti-enzymatic activities against cholinesterases, α-amylase, and α-glucosidase were evaluated using spectrophotometric methods. Notably, the E. brevifolia, E. extensa, E. leptophylla, E. patellaris, and E. woollsiana EOs displayed potent acetylcholinesterase (AChE) inhibition (IC50: 0.25–0.60 mg/mL), with E. lehmannii exhibiting lower activity (IC50: 1.2 mg/mL). E. leptophylla and E. brevifolia showed remarkable α-amylase inhibition (IC50: 0.88 mg/mL), while E. brevifolia and E. leptophylla significantly hindered α-glucosidase (IC50 < 30 mg/mL), distinguishing them from other EOs with limited effects. Additionally, the EOs were assessed for their anti-biofilm properties of Gram-positive (Staphylococcus aureus and Listeria monocytogenes) and Gram-negative (Acinetobacter baumannii, Pseudomonas aeruginosa and Escherichia coli) bacterial strains. The E. extensa EO demonstrated the main antibiofilm effect against E. coli and L. monocytogenes with an inhibition > 80% at 10 mg/mL. These findings could represent a basis for possible further use of Eucalyptus EOs in the treatment of human microbial infections and/or as a coadjutant in preventing and treating Alzheimer’s disease and/or diabetes mellitus.

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Eucalyptus brevifolia F. Muell and Eucalyptus stricklandii Maiden leaves extracts: HPLC-DAD, GC-MS analysis and in vitro biological activities, combined with the principal component analysis

Cited by 7 publications

References 36 publications

Environmental Remediation Promoted by Silver Nanoparticles Biosynthesized by Eucalyptus Leaves Extract

Environmental Remediation Promoted by Silver Nanoparticles Biosynthesized by Eucalyptus Leaves Extract

Comparative Analysis of Organic Extracts Bioactivity from Two Limonium. Mill Species Growing Wild in Tunisian Salty Marshes

Chemical Composition, Antibacterial Properties, and Anti-Enzymatic Effects of Eucalyptus Essential Oils Sourced from Tunisia

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