Eudesmanolides derived from herbolide B

Sesquiterpene lactones from Algerian Artemisia herba-alba

“…Although, the NMR spectral data of 2 was very close with those of the previously synthesized compound (Sokoloff and Sfgal, 1977), compound 2 showed opposite optical rotation sign ½a 25 D ¼ þ4:16 (c = 0.048, CHCl 3 ), while the synthetic compound showed an ½a 25 D of À33 (c = 0.03, CHCl 3 ). Compound 2 was therefore the enantiomer of the reported synthetic compound and was identified as 1b,9b-diacetoxyeudesm-4-en-6b,11bH-12,6-olide, a new natural compound.…”

“…Compound 1 was therefore, identified as 1b,9b-diacetoxyeudesm-3-en-5a,6b,11bH-12,6-olide and was a new natural compound and is reported here for the first time from a natural source (Sokoloff and Sfgal, 1977).…”