Eugenol release and the cytotoxicity of different zinc oxide-eugenol combinations

Meryon, S.D.; Johnson, S.G.; Smith, Audrey

doi:10.1016/0300-5712(88)90053-x

Cited by 34 publications

(10 citation statements)

References 17 publications

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“…Eugenol remains in excess in fresh mixes of zinc oxide-eugenol, where it is not entirely crystallized as zinc eugenolate (22). The surface of the set material readily undergoes hydrolysis, with the release of free eugenol into adjacent fluids (23). It is thought that this free eugenol component can seep out of the setting or set material and cause various cytotoxic effects.…”

Section: Discussionmentioning

confidence: 99%

Volumetric Expansion of Gutta-Percha in Contact with Eugenol

Michaud

Burgess

Barfield

et al. 2008

Journal of Endodontics

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Section: Discussionmentioning

confidence: 99%

Volumetric Expansion of Gutta-Percha in Contact with Eugenol

Michaud

Burgess

Barfield

et al. 2008

Journal of Endodontics

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“…Gutta-percha expands in the presence of eugenol [142,143] which may help to reduce gaps within canals obturated with zinc oxide-eugenol sealer-filled canals caused by the release of eugenol from the set sealer [144], shrinkage [132, 145] or dissolution of sealer over time [146]. Apart from eugenol-induced expansion, closure of interfacial gaps in gutta-percha-filled root canals may also occur by slow, hygroscopic expansion of gutta-percha [147], due to sorption of incompletely removed moisture present within the canal space [148].…”

Section: Recently-introduced Materialsmentioning

confidence: 99%

Ability of new obturation materials to improve the seal of the root canal system: A review

Li¹,

et al. 2014

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Objectives New obturation biomaterials have been introduced over the past decade to improve the seal of the root canal system. However, it is not clear whether they have really produced a three-dimensional impervious seal that is important for reducing diseases associated with root canal treatment. Methods A review of the literature was performed to identify models that have been employed for evaluating the seal of the root canal system. Results and Significance In-vitro and in-vivo models are not totally adept at quantifying the seal of root canals obturated with classic materials. Thus, one has to resort to clinical outcomes to examine whether there are real benefits associated with the use of recently-introduced materials for obturating root canals. However, there is no facile answer because endodontic treatment outcomes are influenced by a host of other predictors that are more likely to take precedence over the influence of obturation materials. From the perspective of clinical performance, classic root filling materials have stood the test of time. Because many of the recently-introduced materials are so new, there is not enough evidence yet to support their ability to improve clinical performance. This emphasizes the need to translate anecdotal information into clinically relevant research data on new biomaterials.

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“…It has been suggested that eugenol has the most detrimental effect on the setting of resin composite materials, because it is known to be a radical scavenger (5). It may penetrate the underlying dentin surface (6)(7)(8)(9), and thus interfere with the polymerization reaction (10)(11)(12).…”

mentioning

confidence: 99%

The effect of zinc oxide‐eugenol on the shear bond strength of a commonly used bonding system

Leirskar

Nordbø

2000

Dental Traumatology

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It has been claimed that eugenol has a detrimental effect on resin composites and dentin bonding systems. The aim of the present study was to examine whether zinc oxide-eugenol (ZOE) cement would reduce the efficacy of a bonding system. Human third molars were selected for the study, and cylindrical posts of a resin composite (Z100) were bonded vertically to a standardized flat dentinal surface, prepared on the buccal surface of the teeth and treated with Scotchbond Multi-Purpose. The tooth surfaces involved were either freshly cut, or had been exposed to ZOE cement for 6 days, with and without a subsequent thorough cleansing with ethanol. The bond strength in shear was measured after 24 hours. The results showed that ZOE cement had no negative effect on the bond strength of the resin composite (Z100) to dentin when this bonding system was used. The mean shear bond value for the specimens covered with ZOE cement for 6 days was 28.1 MPa. For specimens covered with ZOE cement and cleansed with 96% ethanol, the mean shear bond value was 23.5 MPa. The corresponding value for the controls was 19.0 MPa. These findings suggested that eugenol-containing temporary filling materials may be used safely prior to inserting resin based restorative materials, when Scotchbond Multi-Purpose is employed as the bonding agent.

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Eugenol release and the cytotoxicity of different zinc oxide-eugenol combinations

Cited by 34 publications

References 17 publications

Volumetric Expansion of Gutta-Percha in Contact with Eugenol

Volumetric Expansion of Gutta-Percha in Contact with Eugenol

Ability of new obturation materials to improve the seal of the root canal system: A review

The effect of zinc oxide‐eugenol on the shear bond strength of a commonly used bonding system

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