1980
DOI: 10.1248/cpb.28.2546
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Euglobal-III, a novel granulation inhibiting agent from Eucalyptus globulus Labill.

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1986
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Cited by 17 publications
(12 citation statements)
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“…2 Long-chain acyl phloroglucinol compounds.a promoter. 27,140 Recently, we have reported the antileishmanial activity of euglobals G1-G4(130)(131)(132)(133) with IC 50 values against promastigotes of Leishmania donovani of 3.6, 7.1, 3.9 and 12 lg mL −1 respectively 146. The interest in these compounds is shown by numerous synthetic studies involving a variety of different routes.…”
mentioning
confidence: 99%
“…2 Long-chain acyl phloroglucinol compounds.a promoter. 27,140 Recently, we have reported the antileishmanial activity of euglobals G1-G4(130)(131)(132)(133) with IC 50 values against promastigotes of Leishmania donovani of 3.6, 7.1, 3.9 and 12 lg mL −1 respectively 146. The interest in these compounds is shown by numerous synthetic studies involving a variety of different routes.…”
mentioning
confidence: 99%
“…The EtOAc portion was fractionated using a series of chromatographic methods, to obtain compounds 1 – 18 . Of these, 13 known phloroglucinol derivatives were subsequently identified as eucalyptin A ( 6 ), eucalyptin B ( 7 ), macrocarpal A ( 8 ), macrocarpal B ( 9 ), macrocarpal C ( 10 ), macrocarpal D ( 11 ), macrocarpal E ( 12 ), macrocarpal Q ( 13 ), eucarobustol E ( 14 ), euglobal-V ( 15 ), euglobal-III ( 16 ), 1-(2,6-dihydroxy-4-methoxy-3,5-dimethylphenyl)-2-methylbutan-1-one ( 17 ), and 1-(2,4-dihydroxy-6-methoxy-3,5-dimethylphenyl)-3-methylbutan-1-one ( 18 ) . Among them, the (1 R , 4 S , 5 S , 6 R , 7 R , 10 R , 9′ R ) absolute configuration of eucarobustol E ( 14 ) was elucidated for the first time by single-crystal X-ray diffraction with Cu Kα radiation, for which the structure was determined previously by means of NMR spectroscopic analysis …”
Section: Resultsmentioning
confidence: 99%
“…90 2.6.2 Other activities. Euglobal-III (232), euglobal-IVb (241) and euglobal-VII (242) possessed a potent granulation inhibition activity 91,92 whereas (À)-isobicyclogermacrenal (243), isolated from the liverwort Lepidozea vitrea, inhibited the growth of rice. 93 Euglobal-III (232) has also shown strong inhibitory effects on the activation of the Epstein-Barr virus.…”
Section: Lepidozanes and Bicyclogermacrenes (Structures 232-283)mentioning
confidence: 99%