EUS diagnosis of pancreatic lipoma: a case report

Matteo, Francesco Maria Di; Shimpi, Lalit; Pandolfi, M.; Rabitti, Carla; Carboni, Fabio; Gabbrielli, Armando; Costamagna, Guido

doi:10.1016/j.gie.2006.02.015

Cited by 12 publications

(3 citation statements)

References 15 publications

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“…Endoscopic ultrasound–guided, fine-needle aspiration biopsy showing mature fat cells, without any atypia, might be helpful in such cases. 30,31 Recently, we had another case, a 60-year-old woman who presented with lower abdominal pain, and we diagnosed this patient as having LPH, and the patient is currently on watchful waiting, with no changes in the radiological appearance of the lesion in 3-month intervals at 9 months after the original diagnosis.…”

Section: Discussionmentioning

confidence: 99%

Lipomatous Pseudohypertrophy of the Pancreas

Altinel¹,

Basturk²,

Sarmiento³

et al. 2010

Pancreas

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Objectives Owing to the challenges in obtaining pancreatic biopsies, pancreatic resection for presumed malignancy is often performed without histological confirmation. As a result, benign lesions are sometimes surgically removed. One such condition, which is poorly defined in the literature, is referred to as lipomatous pseudohypertrophy (LPH) of the pancreas. Methods Five cases of LPH were analyzed. Results Four patients underwent surgical resection, 3 of which were diagnosed preoperatively by radiology as having ductal adenocarcinoma. The fourth case was correctly interpreted by magnetic resonance imaging as LPH, but the patient underwent resection because of the intractable pain due to pancreatitis. The fifth patient has been placed on watchful waiting. Two tumors were in the pancreatic head, one in the tail, one in the uncinate process, and one demonstrated diffuse involvement. Microscopically, they were characterized as having normal lipocytes without lipoblasts or inflammation. Within the adipose tissue, scattered microscopic foci of pancreatic parenchyma could be seen. Conclusion Lipomatous pseudohypertrophy of the pancreas is a distinct entity characterized by localized/diffuse replacement of pancreatic parenchyma with mature adipose tissue. It forms a pseudotumor that may be difficult to distinguish clinically from pancreatic adenocarcinoma. This entity should be considered when evaluating patients with a new diagnosis of a hypodense pancreatic neoplasm on imaging.

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Section: Discussionmentioning

confidence: 99%

Lipomatous Pseudohypertrophy of the Pancreas

Altinel¹,

Basturk²,

Sarmiento³

et al. 2010

Pancreas

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“…The imaging shows pancreatic lipomas as well defined, homogenous lesions without infiltration of peripancreatic fatty tissue. On ultrasound (US), lipomas are usually hyperechoic, although some lesions may demonstrate hypoechogenicity [4,5]. Legmann et al [6] identified the characteristic features of pancreatic lipoma on CT scans, such as homogeneity, low density of the lesion (amounting from -120 HU to -80 HU), its welldefined borders (without infiltration of intra-and extra-pancreatic structures) and lack of contrast enhancement (central and peripheral) [4][5][6][7][8].…”

Section: Discussionmentioning

confidence: 99%

Rare Case of Pancreatic Lipoma Diagnosed Incidentally on CT Scan and Its Review of Literature

Meena¹

2013

J Clin Case Rep

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“…Liposarcomas of the pancreas are very rare. Only 4 cases have been reported, with poor radiologic data [1,2,4]. PLs are usually smaller than liposarcomas, with thinner bands of collagen defining the tumour.…”

Section: Discussionmentioning

confidence: 99%