EUS-guided brachytherapy

Lah, John J; Kuo, Jeffrey; Chang, Kenneth J.; Nguyen, Phuong

doi:10.1016/j.gie.2005.07.019

Cited by 34 publications

(14 citation statements)

References 23 publications

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“…Feasibility, safety and efficacy of EUS-guided implantation of radioactive seeds have been reported in patients with GI malignancies. [55][56][57][58] EUS-BrTx for a primary tumor has been reported in one small series of patients with head and neck malignancy. 55 EUS-BrTx was successfully used in a patient with recurrent esophageal cancer in perigastric lymph nodes.…”

Section: Eus-guided Brachytherapymentioning

confidence: 99%

Endoscopic ultrasonography‐guided tumor ablation

Lakhtakia

Seo

2017

Digestive Endoscopy

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Real-time guidance of needle advancement has transformed endoscopic ultrasound (EUS) from a diagnostic to an interventional procedure. EUS-guided fine-needle puncture has application in various interventional procedures (drainage of pseudocyst, biliary intervention, and injection of drugs). Celiac plexus or ganglion neurolysis for pain control is the major current EUS-guided fine-needle injection procedure. Feasibility and safety to accurately position needle devices and/or inject under real-time EUS imaging with precise delivery of interventional agent have expanded the use of EUS to ablate tumors. These include radiofrequency ablation, or delivery of fiducial markers, potential antitumor agents, or radioactive seeds, in the cancer mass. Minimally invasive EUS-guided antitumor therapy is primarily used for pancreatic cancer because of better anatomic access (vs other imaging modality) and the dismal prognosis (despite improvements in surgery and chemoradiation). Also, the response to parenteral chemotherapy in pancreatic cancer is poor because of suboptimal drug delivery resulting from hypovascularity and abundant desmoplasia. Other targets for EUS-guided tumor ablation are pancreatic neuroendocrine tumor and pancreatic cyst lesion, which are less aggressive and curable by resection. However, patients non-eligible for surgery may benefit from local EUSguided ablation.

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Section: Eus-guided Brachytherapymentioning

confidence: 99%

Endoscopic ultrasonography‐guided tumor ablation

Lakhtakia

Seo

2017

Digestive Endoscopy

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“…Clinical trials are being performed to study the role of various antitumor agents (being injected, EUS-guided) in unresectable pancreatic cancer [35][36][37]. Lah et al have performed EUS-guided brachytherapy to malignant perigastric lymph node in a patient with recurrent esophageal cancer [38]. Similar case reports of performing EUS-guided ethanol injection into a gastrointestinal tumor or injecting paclitaxel post-ethanol lavage into pancreatic cystic tumors have been published [39,40].…”

Section: Therapeutic Indication For Eusmentioning

confidence: 99%

Role of Endoscopic Ultrasound in Gastrointestinal Surgery

Gouda

Gupta

2011

Indian J Surg

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Endoscopic Ultrasound is an emerging diagnostic tool in the field of Gastrointestinal Surgery. Our review article focuses on role of EUS in staging cancers (esophageal, gastric, biliary and rectal), detection of bilio-pancreatic calculi and diagnosis of chronic pancreatitis. Potential for performing EUS based therapeutic interventions are been explored and looks promising from the initial reports.

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“…Through a large gauge EUS needle, radioactive seeds can be placed into the pancreas with relative safety and minimal tissue reaction. A pilot study in patients with recurrent esophageal cancer in perigastric lymph nodes 97 has demonstrated the feasibility and safety of the procedure. Following the reports of the safety of EUS‐guided insertion of radioactive seeds in an animal model, 98 a recent study with radioactive iodine seeds given in conjunction with chemotherapy has demonstrated tumor remission and improvement in pain 99 .…”

Section: Therapeutic Eusmentioning

confidence: 99%

Interventional endoscopic ultrasonography

Yamao

Bhatia

Mizuno

et al. 2009

J of Gastro and Hepatol

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Endoscopic ultrasonography (EUS) is the combination of endoscopy and intraluminal ultrasonography. This allows use of a high frequency transducer, which, due to the short distance to the target lesion, enables ultrasonographic images of high resolution to be obtained. Endoscopic ultrasonography is now a widely accepted modality for the diagnosis of pancreatobiliary diseases. It can be used to determine the depth of invasion of gastrointestinal malignancies, and often for visualizing lesions more precisely than other imaging modalities. The most important early limitation of EUS was the lack of specificity in the differentiation between benign and malignant changes. In 1992, EUS-guided fine needle aspiration (EUS-FNA) of lesions in the pancreas head has been made possible using a curved linear array echoendoscope. Since then, many researchers have expanded the indication of EUS-FNA to various kinds of lesions and also for a variety of therapeutic purposes. In this review, we particularly focus on the present and future roles of interventional EUS, including EUS-FNA and therapeutic EUS.

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EUS-guided brachytherapy

Cited by 34 publications

References 23 publications

Endoscopic ultrasonography‐guided tumor ablation

Endoscopic ultrasonography‐guided tumor ablation

Role of Endoscopic Ultrasound in Gastrointestinal Surgery

Interventional endoscopic ultrasonography

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