EUS-guided radiofrequency ablation for management of pancreatic insulinoma by using a novel needle electrode (with videos)

EUS-guided Radiofrequency Ablation (EUS-RFA) of Solid Pancreatic Neoplasm Using an 18-gauge Needle Electrode: Feasibility, Safety, and Technical Success

“…Moreover, using percutaneous or EUS guidance, a safe mini-invasive approach can be obtained avoiding laparotomy. To the best of our knowledge, 10 patients underwent pancreatic EUS-RFA with the EUSRA electrode without severe adverse events and with high technical success [5,[18][19][20]. The results of our series confirm the feasibility, safety and local thermal effect of the procedure.…”

“…The needle temperature is affected by the energy used, which determines the ablation volume reached. In previous studies, 50 W was employed for 10/15 seconds, and the procedure was repeated by reinserting the electrode in different zones until the hyperechoic area sufficiently covered the tumor [5,18]. In this study, a slightly different technical approach was used: the electrode was positioned in the middle of the tumor and a lower radiofrequency power (30 W) was applied.…”

Endoscopic Ultrasound-Guided Direct Intervention for Solid Pancreatic Tumors

“…Another study evaluated the feasibility of EUS-RFA for treatment of symptomatic insulinoma by using a different EUS-RFA needle electrode [48]. Three patients with symptomatic pancreatic insulinoma who refused surgical resection underwent EUS-RFA in an observational human case series.…”

Nowotwory neuroendokrynne trzustki — zasady diagnostyki i leczenia (rekomendowane przez Polską Sieć Guzów Neuroendokrynych)

“…It is also possible that in the future endoscopic EUS--controlled ablation of pancreatic NETs, involving the administration of cytotoxic agents or alcohol [181][182][183][184], or using thermoablation [185,186], will become a minimally invasive therapeutic method for patients who cannot be treated surgically (evidence level 4).…”