Evaluación de la respuesta broncodilatadora en pacientes secuelados de adenovirus

Adenovirus pneumonia in infants and factors for developing bronchiolitis obliterans: A 5‐year follow‐up

“…34,35 Moreover, in a short report on 19 children with post-adenovirus LRTIs a significantly higher bronchodilator response was found using IOS versus spirometry (76.4% vs. 29.4%, respectively). 36 Teper et al 37 using tidal and partial forced expiratory flow/volume curves reported a severe and fixed bronchial obstruction in 13 infants with chronic pulmonary disease after severe adenovirus infection; however, we do not know what would be their pulmonary function when they reach pre-school age. Besides, those differences could be explained due to dissimilar population.…”

Postinfectious bronchiolitis obliterans in children: Clinical and pulmonary function findings

“…These features reflect the presence of severe damage in airways as predominant lesion, even if some degree of parenchymal involvement is present as it has been described 16, 17. Other authors have addressed the issue of bronchodilator response in BO, with dissimilar results, and rates of response from 10% to 80% 28, 32, 33. Only 10% of our patients showed positive response to Albuterol, as it could be expected considering the nature of the disease and the severity of our patients.…”

Postinfectious bronchiolitis obliterans in children: the South American contribution

“…In a Chilean study, children with PIBO and a mean age of 5.6 showed a significant increase in resistance in the IOS , similar to their older counterparts using plethysmography. Some debate exists regarding the bronchodilator response to be expected in cases of PIBO, which may vary from case to case . The response, however, will never be complete, because the histological hallmark demonstrates irreversible obstructive changes in PIBO .…”