Evaluación de los cambios precoces de la retina en la enfermedad de Alzheimer y contribución de la papila en la progresión de la enfermedad

Ramirez, J.M.; Salobrar‐García, Elena; Hoz, Rosa de; Pancorbo, Raquel Yubero; López‐Cuenca, Inés; Gregório, Pedro Gil

doi:10.1016/j.regg.2018.04.007

Cited by 1 publication

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“…Studies have shown that long-term cerebral ischemic injury can cause retinal damage, affect vision ( Xie et al, 2016 ). Therefore, ischemia-induced neuronal apoptosis has traditionally shown similarities and the presence of proper cellular communication in the blood–retina barrier (BRB) and blood–brain barrier ( Madeira et al, 2015 ; Ramirez et al, 2018 ).…”

Section: Introductionmentioning

confidence: 99%

Natural products: protective effects against ischemia-induced retinal injury

Xiao

Shi

et al. 2023

Front. Pharmacol.

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Ischemic retinal damage, a common condition associated with retinal vascular occlusion, glaucoma, diabetic retinopathy, and other eye diseases, threatens the vision of millions of people worldwide. It triggers excessive inflammation, oxidative stress, apoptosis, and vascular dysfunction, leading to the loss and death of retinal ganglion cells. Unfortunately, minority drugs are available for treating retinal ischemic injury diseases, and their safety are limited. Therefore, there is an urgent need to develop more effective treatments for ischemic retinal damage. Natural compounds have been reported to have antioxidant, anti-inflammatory, and antiapoptotic properties that can be used to treat ischemic retinal damage. In addition, many natural compounds have been shown to exhibit biological functions and pharmacological properties relevant to the treatment of cellular and tissue damage. This article reviews the neuroprotective mechanisms of natural compounds involve treating ischemic retinal injury. These natural compounds may serve as treatments for ischemia-induced retinal diseases.

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Section: Introductionmentioning

confidence: 99%