EVALUACIÓN DEL RIESGO ACUÁTICO DE SIETE PRODUCTOS FARMACÉUTICOS SOBRE Daphnia magna

Iannacone, José; Alvariño, Lorena

doi:10.21704/rea.v8i1-2.384

Cited by 17 publications

(8 citation statements)

References 19 publications

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“…Acute data exist for cyanobacteria, algae, hydrozoans, rotifers, crustaceans, molluscs, flowering plants and fish. The acute EC50 or LC50 data range from 5.1 mg/L for a marine alga (where TMP would be mostly non-dissociated in view of the basic p H of seawater) [ 137 ] to 296 mg/L for daphnids [ 149 ] for those tests where a concise value is given ( i.e. , not a ‘>highest tested concentration’).…”

Section: Resultsmentioning

confidence: 99%

An Environmental Risk Assessment for Human-Use Trimethoprim in European Surface Waters

Straub

2013

Antibiotics

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An environmental risk assessment (ERA) for the aquatic compartment in Europe from human use was developed for the old antibiotic Trimethoprim (TMP), comparing exposure and effects. The exposure assessment is based on European risk assessment default values on one hand and is refined with documented human use figures in Western Europe from IMS Health and measured removal in wastewater treatment on the other. The resulting predicted environmental concentrations (PECs) are compared with measured environmental concentrations (MECs) from Europe, based on a large dataset incorporating more than 1800 single MECs. On the effects side, available chronic ecotoxicity data from the literature were complemented by additional, new chronic results for fish and other organisms. Based on these data, chronic-based deterministic predicted no effect concentrations (PNECs) were derived as well as two different probabilistic PNEC ranges. The ERA compares surface water PECs and MECs with aquatic PNECs for TMP. Based on all the risk characterization ratios (PEC÷PNEC as well as MEC÷PNEC) and risk graphs, there is no significant risk to surface waters.

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Section: Resultsmentioning

confidence: 99%

An Environmental Risk Assessment for Human-Use Trimethoprim in European Surface Waters

Straub

2013

Antibiotics

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“…Amoxicillin acts against a broad spectrum of gram-positive and gram-negative microorganisms; therefore, it is used as first-line antibiotic both in human medicine and in veterinary medicine in many different countries [56][57][58][59]. Table 1 Besides to the numbers of sales and use of this drug that have been mentioned above, amoxicillin belongs to a group of drugs that are excreted unchanged in urine and faeces at high rates; therefore, it is likely to find amoxicillin concentrations traces in the environment.…”

Section: Amoxicillin Sales and Occurrence In Water Bodiesmentioning

confidence: 99%

Amoxicillin in the Aquatic Environment, Its Fate and Environmental Risk

Elizalde-Velázquez¹,

Gómez-Oliván²,

Galár-Martínez³

et al. 2016

Environmental Health Risk - Hazardous Factors to Living Species

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Amoxicillin is a broad-spectrum antibiotic widely used for treating both human and animal diseases, and it belongs to a group that are excreted unchanged within urine and faeces; therefore, it is possible to find traces of this drug or its degradation products in environmental water bodies. In water, it is rapidly degraded by biotic and abiotic factors, yielding different intermediate products; these are suspected of being more resistant to degradation, and potentially more toxic, than the parent compound. In the water bodies, these compounds may produce toxic effects on the aquatic organisms from different trophic levels and produce an ecological imbalance. Amoxicillin may bioaccumulate in fish muscle tissues, with the possibility of the occurrence of these drugs in food, leading to a passive consumption of this antibiotic resulting in undesirable effects on consumer health such as immunoallergic responses. However, the main problem related with the presence of this antimicrobial compounds in fish tissues is the possibility of inducing bacterial resistance genes. At present, the available scientific knowledge is less than what is needed to fully assess the risks that amoxicillin pose to the environment, and it is still necessary to conduct large amount of research works before a thorough understanding of this severe environmental issue.

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“…Uma das preocupações é com relação a medicamentos que tem resultado em um considerável aporte de substâncias químicas e seus metabólitos nos corpos hídricos. Na literatura há estudos realizados em corpos d'água em que foram encontradas quantidades significativas de medicamentos, entre estes o paracetamol (IANNACONE e ALVARIÑO, 2009;ZACARÍAS et al, 2017). A preparação de materiais finamente particulados como os MOFs, tem atraído interesse de pesquisadores porque esses materiais, além de propriedades superiores aos materiais já conhecidos, podem ser utilizados de uma maneira relativamente simples, possuindo alta eficiência devido à sua grande área superficial (AHMED et al, 2013;QU et al, 2013) Para o estudo da remoção de substâncias de um meio líquido pelas MOFs é necessário entender os fenômenos de adsorção e dessorção e a estrutura da MOF obtida a partir da sua caracterização.…”

Section: Referencial Teóricounclassified

Avaliação Do Manejo Químico De Herbicida Para Controle De Soja E Algodão Resistentes a Glyphosate

Medrado¹,

Medeiros²,

Oliveira³

et al. 2021

O Meio Ambiente E a Interface Dos Sistemas Social E Natural 3

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Direitos para esta edição cedidos à Atena Editora pelos autores.Todo o conteúdo deste livro está licenciado sob uma Licença de Atribuição Creative Commons.Atribuição-Não-Comercial-NãoDerivativos 4.0 Internacional (CC BY-NC-ND 4.0). O conteúdo dos artigos e seus dados em sua forma, correção e confiabilidade são de responsabilidade exclusiva dos autores, inclusive não representam necessariamente a posição oficial da Atena Editora. Permitido o download da obra e o compartilhamento desde que sejam atribuídos créditos aos autores, mas sem a possibilidade de alterá-la de nenhuma forma ou utilizá-la para fins comerciais. Todos os manuscritos foram previamente submetidos à avaliação cega pelos pares, membros do Conselho Editorial desta Editora, tendo sido aprovados para a publicação com base em critérios de neutralidade e imparcialidade acadêmica.A Atena Editora é comprometida em garantir a integridade editorial em todas as etapas do processo de publicação, evitando plágio, dados ou resultados fraudulentos e impedindo que interesses financeiros comprometam os padrões éticos da publicação. Situações suspeitas de má conduta científica serão investigadas sob o mais alto padrão de rigor acadêmico e ético.

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EVALUACIÓN DEL RIESGO ACUÁTICO DE SIETE PRODUCTOS FARMACÉUTICOS SOBRE Daphnia magna

Cited by 17 publications

References 19 publications

An Environmental Risk Assessment for Human-Use Trimethoprim in European Surface Waters

An Environmental Risk Assessment for Human-Use Trimethoprim in European Surface Waters

Amoxicillin in the Aquatic Environment, Its Fate and Environmental Risk

Avaliação Do Manejo Químico De Herbicida Para Controle De Soja E Algodão Resistentes a Glyphosate

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