Evaluación económica de la vacunación frente al neumococo en mayores de 65 años de Castilla y León

López-Gobernado, Miguel; Pérez-Rubio, Alberto; López-García, Eva; Mayo-Íscar, Agustín; Pascual, Carlos Cabezas; Eiros, José María

doi:10.1016/j.regg.2019.05.004

Cited by 3 publications

(2 citation statements)

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“…Based on our data, we see that there is a potential trend to decrease the rate of pneumococcal infections if the guidelines are applied early as already observed in the CAPITA study [13]. This argument is reinforced by studies in our country that have developed a simulated economic model to evaluate the cost of the vaccination strategy in the population over 65 years of age, showing itself to be an efficient strategy with improved quality of life and life expectancy [23,24]. It is remarkable to highlight the low vaccination rate in the high-risk population in our environment, in line with the country's data.…”

Section: Discussionsupporting

confidence: 65%

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Evolution, Clinical and Microbiological Characteristics of Invasive Pneumococcal Disease since the Introduction of the Pneumococcal Conjugate Vaccine 13-Valent in Adults over 18 Years Old

et al. 2021

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Invasive pneumococcal disease (IPD) presents high mortality in the population at risk. The aim of this work is to know the evolution, clinical and microbiological characteristics of IPD in the adult population of Majorca, since the introduction of a public funded program for pneumococcal conjugate vaccine (PCV-13) in the pediatric population in the Balearic Islands in 2016. For this purpose, a retrospective multicenter study was carried out in which all episodes of IPD in adult patients from the four hospitals of the public health system of Majorca were included, comparing the periods between 2012 and 2015 and between 2016 and 2019. Clinical variables, serotypes and antibiotic sensitivity were collected. There were 498 cases of IPD; 56.8% were male with a mean age of 67 (standard deviation: 16). Most infections were bacterial pneumonias (73.7%). Of the total cases, 264 (53%) presented complications. Of the 498 cases, 351 strains were obtained, of which 145 (41.3%) belong to vaccinal serotypes (included in the PCV-13 vaccine) and 206 (58.7%) to non-vaccinal serotypes (not included in the PCV-13 vaccine). The percentage of IPD caused by vaccinal serotypes was lower in the second period (47.8% vs. 34.5%; p = 0.012).

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Section: Discussionsupporting

confidence: 65%

“…It is remarkable to highlight the low vaccination rate in the high-risk population in our environment, in line with the country's data. More and more studies are emerging with evidence in cost-effective terms in favor of health interventions that implement vaccination in the adult population [24].…”

Section: Discussionmentioning

confidence: 99%