One of the strategies to increase the cattle population in Indonesia is the IB (artificial insemination) method. The AI program's improvement of reproductive efficiency can use the estrus synchronization method. The purpose of this study was to see the effect of body weight and body condition score on the estrus synchronization response with the brand "lutelyse." This research was conducted in Senggreng Village, Sumberpucung District, Malang Regency, by conducting field experiment research methods. This study took a sample of 21 female broodstock synchronized with PGF2α as much as 2 ml, which was then carried out by observing estrus behavior for 24 hours after synchronization. Based on the study results, the percentage of oestrus in cows with BCS 4, which is 76.92%, is lower than cows with BCS 5, which is 100%. For the synchronization distance with the onset of estrus in BCS 4 cattle, namely 3802.92 ± 1007.80 (minutes) and BCS 5, namely 4081 ± 884.91 (minutes) with the results of the conception rate of BCS 4 cattle of 38.46% and BCS 5 of 50%. This study concludes that BCS 5 has a higher success rate than BCS 4.