Evaluate Clinical Efficacy of Bioceramic Technology on Psychopathically Related Spasmodic Torticollis Using Motion Measurements, Computerized Analysis of Facial Emotions and Speech Signal Features

Abstract

Objective: Spasmodic torticollis is a debilitating neurological movement disorder associated with somatization, obsessive-compulsive, interpersonal sensitivity, depression, and anxiety. Usually, clinician had difficulty to precisely and quantitatively describe clinical outcomes using measurements of patients’ facial and neck movements. Methods: Motion speed changes and direction complexity, computerized facial emotion and assessment, measurement of speech signal features are the quantitative measurements of patients’ head motions, facial expressions, and speech signal features analysis were used to assess clinical effects of bioceramic resonance and photoluminescence of bioceramics (BR&PLB) treatment of psychopathically related spasmodic torticollis. Results: After BR&PLB treatment, there were significant improvements in involuntary movements of patients with spasmodic torticollis measured by motion speed changes and direction complexity (MSCDC). Furthermore, a computerized facial emotion assessment (CFEA) showed that patients expressed greater positive emotions after treatment. Finally, we also performed quantitative assessments on voice analysis of speech signal features (SSF). Conclusions: Our study had achieved three major factors: (i) the clinical efficacy of BR&PLB on psychopathically related spasmodic torticollis; (ii) motion manifestations of spasmodic torticollis in “speed” and “direction” of muscular movements as assessed using “motion measurements” of a computer vision system; and (iii) psychological and emotional factors being directly correlated with the severity of spasmodic torticollis which improved after BR&PLB, and could be qualitatively assessed using FaceReader. This study encourages further investigations of the clinical efficacy of Bioceramic technology on psychopathically related repetitive behavior disorders, and demonstrates effectiveness of MSCDC, CFEA and SSF in providing quantitative assessments of emotion.

Complementary and Alternative Treatment of Using BIOCERAMIC related Technology on Mental and Psychiatric Related Disorders

“…There were studies of patients with depression had found acoustic features, could be useful as biomarkers for evaluation of symptom severity and treatment efficacy for depression. In our study, it was indicated a significant decrease of fundamental frequency of the patient's SSF after the treatments of BR&PLB [12,16].…”

“…By selecting specific tempo frequencies of sound wave, device of BIOCERAMIC resonance produces vibration of specific meridian channels described by Traditional Chinese medicine (TCM), which brings to clinical benefits [7,8]. Our study was then begun from in vitro cell study of material science, and then go through different animal and human trials [6], There were under permissions with a series of IRB approvals, include Taipei Medical University & Hospital, Taipei Hospital and Taoyuan General Hospital [6][7][8][9][10][11][12][13][14]. In this review article, we present our experience base on clinical experimental results to explain and describe clinical efficacy BIOCERAMIC related technology that apply to mental and psychiatric related disorders [9][10][11][12][13][14].…”

“…Spasmodic torticollis is a kind of debilitating neurological movement disorder with tonic and phasic involuntary movements of the cervical musculature cause intermittent, involuntarily, or sustained deviations and jerky movements of the head and neck. The disorder is always associated with mental problems of somatization, obsessive-compulsive, interpersonal sensitivity, depression, and anxiety [12]. There was a 61-year-old male, who initially began suffering from spasms of his right face and sternocleidomastoid muscle 34 years ago.…”

Synergistic Impact of 'Bioceramic Resonance and Photoluminescence' with Visual/Auditory Thematic Stimulation System: Evaluating Effects on Body, Emotion, Perception and Consciousness Assessment (Preprint)

“…Our exploration of BR-related technology in mental and psychiatric disorders contributed to a comprehensive understanding of its versatility in mental health treatment. Studies on psychopathically related spasmodic torticollis [7], drug withdrawal symptoms [6], and extrasensory perception [9] provided quantitative frameworks for assessing clinical efficacy, collectively demonstrating BR's impact on neurological movement disorders and its potential applications in substance abuse treatment.…”

“…Our investigation commenced with in vitro cell studies in material science and advanced through a series of animal and human trials. All these phases were conducted following approved Institutional Review Board (IRB) protocols from reputable institutions, including Taipei Medical University & Hospital, Taipei Hospital, and Taoyuan General Hospital [3,5,6,7,8,9,10,12,16,17 ].…”