Evaluating Clinical Features in Intracavitary Uterine Pathologies among Vietnamese Women Presenting with Peri-and Postmenopausal Bleeding

Abstract

Background: Intracavitary uterine pathologies (IUPs) may be resulting in vaginal bleeding in perimenopausal and postmenopausal women. Especially, malignant disease needed to be investigated due to its adverse impact on the quality of mid-life women as well as the burden of health-care costs in low- and middle-income countries such as Vietnam. Objective: Thereby, through this study, we aimed to assess the major clinical features of IUPs in women with perimenopausal and postmenopausal bleeding women. Materials and Methods: This was a cross-sectional observational study at Hue University Hospital and Hue Central Hospital from June 2016 to June 2019. The study enrolled 150 women above 40 years old involving with intrauterine bleeding. Results: The mean age of the study population was 51.51 ± 7.65. The most common symptom in perimenopausal women was menorrhagia, up to 62.2% of cases. In addition to intrauterine bleeding, there were 54.7% of cases had at least one other functional symptom, they were pale skin (35.9%), and lower abdominal pain (31.3). Endometrial hyperplasia (EH) was the most common pathology in both groups with perimenopausal and postmenopausal bleeding (PMB), respectively, 66.7% and 51.7%. In PMB group, endometrial cancer (EC) occupied approximately 38.3% following EH. Our study revealed age, menstrual characteristics, and diabetes in relation to malignant disease. Other factors seemed to be less associated with EC. Conclusions: Menorrhagia was the most common type of abnormal uterine bleeding in perimenopausal women. Besides vaginal bleeding, others symptoms such as pale skin, pelvic pain, and fatigue were also common. Length day and blood loss before hospitalization in perimenopausal women were greater significantly than that in postmenopausal women. Age, menstrual characteristics, and diabetes increased the risk of EC in women with PMB.

Retraction

“…The original article titled “Combination of B-mode ultrasound and doppler ultrasound in approaching to uterine intracavitary pathologies among women above 40 years with abnormal uterine bleeding: A multicenter-based study from vietnam” published in Journal of Mid-Life Health, on page 145-151, Issue 2, Volume 13, 2022,[ 1 ] is being retracted because the authors found certain ethical concerns and the article has sections of content with high rate of similarity.…”

Contributing factors related to abnormal uterine bleeding in perimenopausal women: a case–control study

“…The duration of bleeding and the volume of blood loss prior to hospital admission are notably higher in perimenopausal individuals compared with their postmenopausal counterparts. Factors including age, menstrual characteristics, and diabetes heighten the susceptibility to endometrial cancer in women experiencing postmenopausal bleeding [ 18 ].…”

Analysis of Characteristics of Endometrial Carcinoma in Peri- and Postmenopausal Women with Abnormal Uterine Bleeding

“…This will enable a preliminary prediction of the occurrence and prognosis of endometrial carcinoma, with a specific focus on the most common abnormal clinical manifestations of uterine bleeding. Additionally, it will provide clinical data support for the early diagnosis and treatment of endometrial carcinoma [18,19]. Due to the retrospective nature of this study, no accurate data on the duration of menopause and current computerized bleeding were collected.…”