Evaluating genetic differentiation of Anopheles arabiensis in relation to larval habitats in Kenya

Kamau, Luna; Munyekenye, Godwil; Vulule, John; Lehmann, Tovi

doi:10.1016/j.meegid.2006.11.006

Cited by 11 publications

(14 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, An. arabiensis shows no population division (Kamau et al, 2007). The possible confounding effect of gene(s) conferring insecticide resistance on traits such as larval predator avoidance and longevity remains unknown because of the high frequency of the kdr resistance mutation in many populations of the S form, and because other genes conferring insecticide resistance, most of which are unknown, cannot be ruled out.…”

Section: Discussionmentioning

confidence: 99%

The molecular forms of Anopheles gambiae: A phenotypic perspective

Lehmann

Diabaté

2008

Infection, Genetics and Evolution

Self Cite

152

189

View full text Add to dashboard Cite

The African malaria mosquito Anopheles gambiae is undergoing speciation, being split into the M and S molecular forms. Speciation is the main process promoting biological diversity, thus, new vector species might complicate disease transmission. Genetic differentiation between the molecular forms has been extensively studied, but phenotypic differences between them, the evolutionary forces that generated divergence, and the mechanisms that maintain their genetic isolation have only recently been addressed. Here, we review recent studies suggesting that selection mediated by larval predation and competition promoted divergence between temporary and permanent freshwater habitats. These differences explain the sharp discontinuity in distribution of the molecular forms between rice fields and surrounding savanna, but they can also explain the concurrent cline between humid and arid environments due to the dependence on permanent habitats in the latter. Although less pronounced, differences in adult body size, reproductive output, and longevity also suggest that the molecular forms have adapted to distinct niches. Reproductive isolation between the molecular forms is achieved by spatial swarm segregation, although within-swarm mate recognition appears to play a role in certain locations. The implications of these results to disease transmission and control are discussed and many of the gaps in our understanding are highlighted.

show abstract

Section: Discussionmentioning

confidence: 99%

The molecular forms of Anopheles gambiae: A phenotypic perspective

Lehmann

Diabaté

2008

Infection, Genetics and Evolution

Self Cite

152

189

View full text Add to dashboard Cite

show abstract

“…(Zheng et al 1993, Zheng et al 1996) and have been used to elucidate the population structure and gene flow within and between members of the An. gambiae complex (Kamau et al 1999, Kamau et al 2007, Moreno et al 2007). Most of these studies have mainly been conducted on An.…”

mentioning

confidence: 99%

“…Existing literature on An. arabiensis has revealed the absence of subpopulation differentiation in relation to larval habitat exploitation (Kamau et al 2007) as well as the lack of annual bottlenecks in response to changes in weather conditions (Simard et al 2000, Kent et al 2007). However, there is evidence in support of (Simard et al 1999, Donnelly and Townson 2000) and against (Kamau et al 1999, Kent et al 2007) restricted gene flow among widely separated populations.…”

mentioning

confidence: 99%

Population Genetic Structure of <I>Anopheles Arabiensis</I> (Diptera: Culicidae) in a Rice Growing Area of Central Kenya

Muturi

Kim

Baliraine

et al. 2010

View full text Add to dashboard Cite

Studies were conducted to examine the population genetic structure of Anopheles arabiensis (Patton) in Mwea Rice Irrigation Scheme and surrounding areas in Central Kenya, under different agricultural systems. This study was motivated by observed differences in malaria transmission indices of An. arabiensis within the scheme compared with adjacent nonirrigated areas. Agricultural practices can modify local microclimate and influence the number and diversity of larval habitats and in so doing may occasion subpopulation differentiation. Thirty samples from each of the three study sites were genotyped at eight microsatellite loci. Seven microsatellite loci showed high polymorphism but revealed no genetic differentiation (FST = 0.006, P = 0.312) and high gene flow (Nm = 29-101) among the three populations. Genetic bottleneck analysis showed no indication of excess heterozygosity in any of the populations. There was high frequency of rare alleles, suggesting that An. arabiensis in the study area has a high potential of responding to selective pressures from environmental changes and vector control efforts. These findings imply that An. arabiensis in the study area occurs as a single, continuous panmictic population with great ability to adapt to human-imposed selective pressures.

show abstract

“…Such phenotypic and molecular identity was noticed among Chinese, Japanese and Indian populations of B. mori (Datta 1984;Pradeep et al 2005b). Moreover, continuous inbreeding could have contributed to homozygosity and loss of rare alleles resulted in loss of genetic variations as noticed in eri populations (Debaraj et al 2002) and other insects (Kamau et al 2007;Arunkumar et al 2009). Additionally, homozygosity of genes controlling fitness traits has a powerful effect on viability compared to heterozygous state (Strunnikov 1995) which ought to be the reason for high survival (80 to 91%) of eri silkworms in the fluctuating environmental conditions of varying altitudes.…”

Section: Resultsmentioning

confidence: 99%

Genetic evaluation of eri silkworm Samia cynthia ricini: ISSR loci specific to high and low altitude regimes and quantitative attributes

et al. 2011

View full text Add to dashboard Cite

Genetic structure of populations is under constant pressure from varying geographical conditions that induce phenotypic plasticity in insects. Spatial distribution of 15 populations of Indian eri silkworm, Samia cynthia ricini originated at various altitudes of sub Himalayas based on Euclidean distance realized from yield attributes showed two population clusters irrespective of their place of origin and altitude. However, DNA amplification profile by inter SSR (ISSR) markers showed genetic variations among the populations depend on low and high altitudes. One ISSR locus each specific to high and low altitude population was identified. The locus from high altitude showed deviation from Hardy-Weinberg equilibrium but that from low altitude was in neutrality suggests that the high altitude loci could be under pressure from the altitudinal variations. In association with different yield traits, 18 loci were identified. Of which, three markers showed association with more than one trait indicative of pleiotropic influence. Stepwise addition of markers enhanced the correlation between markers and the associated trait pointed to polygenic influence. Association of markers with altitude and yield traits suggests an imperative relation of rare genetic loci with gene-environment interaction and phenotypic variability in S. c. ricini.

show abstract

Evaluating genetic differentiation of Anopheles arabiensis in relation to larval habitats in Kenya

Cited by 11 publications

References 25 publications

The molecular forms of Anopheles gambiae: A phenotypic perspective

The molecular forms of Anopheles gambiae: A phenotypic perspective

Population Genetic Structure of <I>Anopheles Arabiensis</I> (Diptera: Culicidae) in a Rice Growing Area of Central Kenya

Genetic evaluation of eri silkworm Samia cynthia ricini: ISSR loci specific to high and low altitude regimes and quantitative attributes

Contact Info

Product

Resources

About