Evaluating long-term patient-centered outcomes following prostate cancer treatment: findings from the Michigan Prostate Cancer Survivor study

Darwish-Yassine, May; Berenji, Manijeh; Wing, Diane; Copeland, Glenn; Demers, Raymond Y.; Garlinghouse, Carol; Fagerlin, Angela; Newth, Gail; Northouse, Laurel; Holmes‐Rovner, Margaret; Rovner, David R.; Sims, Jerry E.; Wei, John T.

doi:10.1007/s11764-013-0312-8

Cited by 46 publications

(45 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In addition, 75% of men reported at least one 'current' physical symptom (Gavin et al, 2015). The most common side-effects after PCa treatment are sexual dysfunction (in particular erectile dysfunction and libido loss) urinary incontinence, and bowel problems (Miller et al, 2005, King et al, 2012, Darwish-Yassine et al, 2014, Potosky et al, 2004.…”

Section: Introductionmentioning

confidence: 99%

Factors associated with current and severe physical side-effects after prostate cancer treatment: What men report

et al. 2016

View full text Add to dashboard Cite

We identified patient and disease characteristics associated with (1) “current” physical side‐effects of any severity; and (2) “severe” physical side‐effects “ever” experienced by 3,348 (54%) prostate cancer (PCa) survivors in Ireland diagnosed 2–18 years previously. Postal questionnaires collected symptoms at diagnosis, post‐biopsy complications, comorbidities, primary treatments and physical side‐effects post‐treatment (urinary incontinence, erectile dysfunction, libido loss, bowel problems, breast changes, hot flushes, and fatigue, “ever” and “current” at time of questionnaire completion). Men were grouped by “early” (localised) and “late” (locally advanced/advanced) disease at diagnosis. Multivariable logistic regression analysis identified patient and disease‐related factors associated with post‐treatment side‐effects. Complications post‐biopsy were associated with higher risk of “current” libido loss and impotence. Radical prostatectomy was associated with higher risk of “current” and “severe” incontinence, libido loss and impotence in both early and late disease. In early disease, brachytherapy was associated with lower risk of “current” fatigue and “severe” impotence. Comorbidities were associated with higher risk of “current” experience of four side‐effects (incontinence, libido loss, bowel problems, fatigue). Men on active surveillance/watchful‐waiting reported lower risk of sexual dysfunction. These findings could inform development of tailored information on side‐effects, which, in turn, could inform treatment decision‐making and post‐treatment monitoring.

show abstract

Section: Introductionmentioning

confidence: 99%

Factors associated with current and severe physical side-effects after prostate cancer treatment: What men report

et al. 2016

View full text Add to dashboard Cite

show abstract

“…The pioneer teams in the field are well aware of the possibility of "very late" relapses, up to 10-15 years after treatment, while information about very late toxicity is still scarce in the literature, and while the long-term quality of life of the patients is becoming an obvious challenge [11,12].…”

Section: Introductionmentioning

confidence: 99%

Long-term results of permanent implant prostate cancer brachytherapy: A single-institution study of 675 patients treated between 1999 and 2003

Cosset

Flam

Belin

et al. 2016

Cancer/Radiothérapie

View full text Add to dashboard Cite

“…In some cases, clinicians may feel uncomfortable or ill equipped to handle these sensitive topics. (12, 13) As such, prostate cancer survivors may engage in symptom self-management by seeking health information, and then, caring for themselves. For cancer patients in general, having the appropriate amount of cancer-relevant information from a variety of sources improves patient outcomes across the cancer control continuum.…”

Section: Introductionmentioning

confidence: 99%

Symptom burden and information needs in prostate cancer survivors: a case for tailored long‐term survivorship care

et al. 2015

Self Cite

View full text Add to dashboard Cite

Objectives To determine the relationship between long-term prostate cancer survivors’ symptom burden and information needs. Subjects/patients and methods We used population-based data from the Michigan Prostate Cancer Survivor Study (n=2,499). We examined unadjusted differences in long-term information needs according to symptom burden and performed multivariable logistic regression to examine symptom burden and information needs adjusting for patient characteristics. Results High symptom burden was reported across all domains (sexual 44.4%, urinary 14.4%, vitality 12.7%, bowel 8.4%, emotional 7.6%) with over half of respondents (56%) reporting they needed more information. Top information needs involved recurrence, relationships, and long-term effects. Prostate cancer survivors with high symptom burden more often searched for information regardless of domain (p<0.05). High sexual burden was associated with greater need for information about relationships (OR=2.05; 95% CI 1.54–2.72) and long-term effects (OR=1.60; 95% CI 1.23–2.07). High bowel burden was associated with greater information need for long-term effects (OR=2.28; 95% CI 1.43–3.63). Conclusions Long-term prostate cancer survivors with high symptom burden need more supportive information. Tailoring information to these needs may be an efficient approach to support the growing population of long-term prostate cancer survivors.

show abstract

Evaluating long-term patient-centered outcomes following prostate cancer treatment: findings from the Michigan Prostate Cancer Survivor study

Abstract: This study is needed to ensure that the post-treatment symptoms of prostate cancer survivors are properly addressed and managed by healthcare providers over the long term.

Cited by 46 publications

References 34 publications

Factors associated with current and severe physical side-effects after prostate cancer treatment: What men report

Factors associated with current and severe physical side-effects after prostate cancer treatment: What men report

Long-term results of permanent implant prostate cancer brachytherapy: A single-institution study of 675 patients treated between 1999 and 2003

Symptom burden and information needs in prostate cancer survivors: a case for tailored long‐term survivorship care

Contact Info

Product

Resources

About