Evaluating memory dysfunction after spinal anesthesia among patients undergoing elective surgery: Descriptive-analytical study

Vahabi, Sepideh; Karimi, Arash; Beiranvand, Siavash; Babaei, Simin

doi:10.1016/j.amsu.2021.01.034

Cited by 9 publications

(5 citation statements)

References 24 publications

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“…A meta-analysis by He et al, including 8 randomized control trials and 905 subjects reported that ondansetron significantly reduces the incidence of post-anesthesia shivering [20]. Other meta-analysis studies also concluded that ondansetron prevents postoperative shivering and the effects of ondansetron and meperidine are similar [8,9]. In a randomized placebo-controlled trial targeting the comparative effects of ondansetron and meperidine on postoperative shivering following general anesthesia, it is reported that the incidence of shivering in ondansetron and meperidine was significantly lower as compared to the placebo group [21,22].…”

Section: Discussionmentioning

confidence: 99%

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Cross-sectional Study on Effects of Ondansetron and Meperidine in the Prevention of Postoperative Shivering after Spinal Anesthesia

Vahabi¹,

Beiranvand²,

Karimi³

et al. 2021

TOATJ

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Purpose: Post-anesthesia shivering is one of the most common problems after surgery and may lead to multiple complications such as hypoxemia, lactate acidosis and catecholamine release. The purpose of this study was to compare the effects of intravenous meperidine and ondansetron on postoperative shivering in patients having an elective cesarean section under spinal anesthesia. Design: Cross-sectional study Methods: In this cross-sectional study, 105 patients with the age of 18-45 years and ASA class I-II undergoing elective cesarean section were randomly assigned into three groups. Group O was administered 8mg ondansetron, group M patients were given 0.4mg/kg meperidine and group P was placebo that was administered with 2cc of saline intravenously after the delivery. The incidence and intensity of shivering and postoperative nausea was monitored and recorded by the trained nurse. The data obtained was analyzed using SPSS v18. Results: All three groups (n=35) had no significant difference in terms of age, weight and time of spinal anesthesia. Postoperative shivering was reported in 4 patients (11.4%) in group A and 3 patients (8.6%) in group B and in 14 patients (40%) in group C. The incidence of postoperative shivering was significantly less in groups A and B as compared to the placebo, p=0.03. The intensity of shivering was greater in group C as compared to groups A and B, p=0.01. The incidence and intensity of postoperative nausea was significantly less in group A, p=0.03, p<0.001, respectively, while no difference was reported in groups B and C, p<0.05. Conclusion: 8mg ondansetron and 0.4 mg/kg of meperidine are equally effective in managing postoperative shivering; however, ondansetron has an additional effect of reducing the incidence of postoperative nausea among patients undergoing caesarean section with spinal anesthesia.

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Section: Discussionmentioning

confidence: 99%

“…Meperidine is one of the most effective anti-shivering agents that acts on thermoregulation centers or opioid receptors to regulate shivering. 0.4mg/kg of meperidine is an optimal dose in the management of postoperative shivering [7,8].…”

Section: Introductionmentioning

confidence: 99%

Cross-sectional Study on Effects of Ondansetron and Meperidine in the Prevention of Postoperative Shivering after Spinal Anesthesia

Vahabi¹,

Beiranvand²,

Karimi³

et al. 2021

TOATJ

Self Cite

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“…Spinal anesthesia is known to be associated with a greater Apgar score, compared to general anesthesia 3 , 4 . Unstable hemodynamics such as hypotension and bradycardia are common complications of spinal anesthesia 5 . Pruritus and postoperative shivering is also common with the use of spinal anesthesia 6 .…”

Section: Introductionmentioning

confidence: 99%

Effects on ondansetron of post-dural puncture headache after cesarean section under spinal anesthesia

Baharvand,

Vahabi,

Beiranvand

2024

Annals of Medicine &Amp; Surgery

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Background: Spinal anesthesia is commonly performed for cesarean section, however, post-dural puncture headache (PDPH) is one of its most common adverse effects. Ondansetron is an antiemetic for cancer treatment and analgesia-induced nausea and vomiting. In this study, we aim to evaluate the effect of postoperative ondansetron on PDPH. Methods: In this randomized controlled clinical trial study, 120 Pregnant patients are ASA ll, undergoing elective cesarean section, were randomized into two groups (placebo or study). The patients in the study group , immediately after the birth of a baby and 24 hours after the operation, received ondansetron 4 mg IV while the placebo group received a placebo. The severity and incidence of headache, postoperative nausea and vomiting, dizziness, neck and lower back pain and the use of analgesia was assessed in the two groups. Results: The significant meaning of the time effect (P<0.001) indicated that regardless of the group, for each unit increase in time, the chance of developing a headache increased by 23%, which was statistically significant. Also, the significant meaning of the group effect indicated that regardless of time, patients who did not take indomethacin had approximately 4.11 times higher chances of developing a headache compared to those who received the medication, which was statistically significant (P=0.004). Conclusion: The administration of ondansetron significantly reduces the occurrence of post-spinal anesthesia headaches and neck pain. There was no significant difference in headache severity between the two study groups.

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“…Cesarean section (C-section) is one of the most common surgeries in obstetrics and gynecology, which is performed from 58 % in developing countries to 19 % in developed countries [ 1 , 2 ]. Causes of cesarean section include history of previous cesarean section, fetal distress, fetal progression, cephalopelvic disproportion (CPD), and prenatal bleeding [ 3 , 4 ]. Postoperative care following C-section includes proper nutrition and adequate hydration [ 5 ].…”

Section: Introductionmentioning

confidence: 99%

Effect of caffeine on postoperative bowel movement and defecation after cesarean section

Zamanabadi

Alizadeh

Gholami

et al. 2021

Annals of Medicine &Amp; Surgery

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Introduction and Importance: Inadequate bowel movement after cesarean section (C-section) can delay the intake of solid diet. Coffee is reported to have beneficial effects on bowel motility after the surgery. This study is designed to evaluate the effects of coffee on bowel movement and defecation following C-section. Methods In this randomized clinical trial study, women undergoing elective C-section at the hospital of (XXX) during 2019–2020 were included. Following the surgery, the patients were divided in case (coffee) and control (water) group. At three different interval after the surgery, 111 ml of coffee or water was given to these patients. After the intervention, time of bowel movement, first defecation, body mass index (BMI), age, gestational age, parity and gravidity were recorded and evaluated between the two groups. Results Of total 36 patients (18 in study and control group, respectively), the mean age, gravidity, parity, BMI and gestational age was not significantly different, p-value<0.05. The mean onset of bowel movements in case group was 14.56 h and control group was 16.83 h and the first defecation after cesarean section in case and control group was 27.78 and 31.67 h, respectively. The two groups were significantly different in both the terms, p-value = 0.042 and p-value = 0.002, respectively. Conclusion The postoperative bowel movement and defecation time is shorter with the intake of coffee among patients undergoing C-section.

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Evaluating memory dysfunction after spinal anesthesia among patients undergoing elective surgery: Descriptive-analytical study

Cited by 9 publications

References 24 publications

Cross-sectional Study on Effects of Ondansetron and Meperidine in the Prevention of Postoperative Shivering after Spinal Anesthesia

Cross-sectional Study on Effects of Ondansetron and Meperidine in the Prevention of Postoperative Shivering after Spinal Anesthesia

Effects on ondansetron of post-dural puncture headache after cesarean section under spinal anesthesia

Effect of caffeine on postoperative bowel movement and defecation after cesarean section

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