Evaluating the Etiologies of Burning Mouth Symptom in Patients of Shiraz Dental School from 2007 to 2015

BioMed Research International

Azad

2020

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Background. Oro-dental diseases are prevalent in chronic liver failure (CLF) patients. The aim of this study was to evaluate the quality of life associated with oral health in candidates for liver transplant surgery. Materials and Methods. The demographic information of 105 end-stage liver cirrhotic patients was collected. All patients were ordered a panoramic view for pretransplant dental evaluation. The DMFT (decayed-missing-filled tooth) index was calculated for dental examination. The model for end-stage liver disease (MELD) was used for the severity of liver disease. The OHIP-14 (Oral Health Impact Profile) questionnaire and GOHAI (Geriatric Oral Health Assessment Index) questionnaire were applied to evaluate the impact of oral disease on the quality of life. Results. A total of 79 patients thoroughly completed the questionnaires; 79.7% were male, 32.9% were over 50, and 25.3% were less than 30 years old. Further, 12.7% smoked, 2.5% were illiterate, 64.6% had not finished school, and 10.1% had university degrees. Almost half of the cirrhotic patients were suffering from the disease for more than 3 years. Most complaints reported by the patients as “very often” were becoming self-conscious (13.9%) and being uncomfortable when eating any foods (13.9%) followed by feeling tense (12.8%). There was no significant difference between gender, smoking, age, and MELD score based on quality of life (OHIP and GOHAI) ( P > 0.05 ). The level of education ( P = 0.020 ), duration of disease ( P = 0.017 ), and DMFT index ( P = 0.039 ) had a significant impact on oral health-related quality of life in CLF patients. An inverse relationship was seen between the DMFT index and the quality of life. Conclusion. Oral health has a high impact on the quality of life of cirrhotic patients. The psychological dimension of oral health is the most debilitating factor affecting the quality of life. This shows the importance of professional oral care, oral health, and self-care education in this group of patients.

Section: Introductionmentioning

confidence: 99%

Oral Health-Related Quality of Life in Chronic Liver Failure Patients Measured by OHIP-14 and GOHAI

BioMed Research International

Azad

2020

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“…4 In the oral cavity, C. albicans can be seen as, various forms, such as pseudomembranous candidiasis, chronic plaque-type and nodular candidiasis, erythematous candidiasis, denture stomatitis, angular cheilitis, median rhomboid glossitis, and oral candidiasis associated with human immunodeficiency virus infection. [5][6][7] Before starting antifungal medication, it is necessary to eliminate any predisposing factor. Local…”

Section: Introductionmentioning

confidence: 99%

“…7,8 Antifungal drugs have a primary role in such cases. The most commonly used antifungal drugs belong to the groups of polyenes and azoles.…”

Section: 5005/jp-journals-10024-2225mentioning

confidence: 99%

Antifungal Activity of Xylitol against Candida albicans: An in vitro Study

Talattof

Azad

The Journal of Contemporary Dental Practice

et al. 2018

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Aim:The most common fungal infection among human population is candidiasis, the etiology of which is mostly Candida albicans. As a result of a disrupted balance of the normal flora or a compromised immune system, Candida species can become pathogenic. Various in vitro surveys have shown that glucose intake is a promoter of C. albicans growth, whereas in vivo studies have found that xylitol can decrease the risk of candidiasis and angular cheilitis. Hence, we aimed to evaluate for the first time the inhibitory effects of xylitol on C. albicans by assessing its minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC). Materials and methods:The standard strain of C. albicans was acquired. The fungi were incubated in supplemented brain-heart infusion broth for 48 hours at 37°C. The MIC was measured according to the Clinical and Laboratory Standards Institute (CLSI) M100-S24 standard. Microdilution method was applied using 360-µL sterilized polystyrene flat-bottomed 96-well plates. The antimicrobial effects were examined by the microbroth dilution method according to the CLSI M100-S24 standard. Results:The MIC of xylitol for C. albicans was found to be 20 × 10 4 µg/mL. Furthermore, the concentration of 40 × 10 4 µg/mL with a decrease of 99.95% in the colony-forming units (CFUs) of the microorganism was found to be the MFC of xylitol for C. albicans. Clinical significance: By knowing the MIC and MFC of xylitol, this substance can be effectively used in products aimed to cure this fungal infection. Conclusion:

“…This lesion can be very irritating and disabling due to the severe pain and unappealing appearance. (3,4) Common drugs such as acyclovir and valacyclovir and less common medication such as cytarabine and vidarabine are used in the treatment of viral herpes infections. Acyclovir is widely used and it is the selective treatment for herpes labialis infections.…”

mentioning

confidence: 99%

Comparative study of serum zinc concentration in recurrent herpes labialis patients and healthy individuals

et al. 2020

Preprint

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Background: Recurrent herpes labialis (RHL) is one of the most common recurrent infective vesiculoulcerative lesions. Topical and systemic administration of Zinc compounds has been found to have preventive and therapeutic effects. The purpose of this article is to evaluate the serum level of zinc in patients with RHL and healthy individuals.Methods: This cross-sectional study was performed on 43 patients with the history of recurrent herpers labialis and 42 healthy subjects with no history of the lesion. Blood samples were taken and serum zinc level was measured. Chi-Square test was used to compare the qualitative relationships and to compare the quantitative relationships independent T-test was used. To observe the relationship of quantitative factors including serum zinc level, the number of relapses and recovery rates correlation test was taken.Results: The results show that serum zinc level has no significant difference in healthy subjects and patients (p> 0.05). Also, zinc level was not related to age and sex factors and frequency of relapse (P> 0.05). But surprisingly in the patients group, there was a significant relationship between zinc level and recovery period. As the serum zinc level was lower, the duration of recovery was significantly higher (p =0.009). Conclusion:The results of this study indicate that zinc deficiency is a risk factor for increasing the duration of herpes labialis lesions. Therefore, the evaluation of serum zinc level in subjects with recurrent herpes labialis and subsequent administration of zinc is recommended in such patients. Background:Herpes simplex virus type 1 (HSV-1) a member of the herpes virus family is the etiologic factor of a variety of diseases. It generally affects the upper parts of the human body. The primary infection appears after fluid or skin contact with contaminated individuals. The virus tends to remain in the sensory ganglions or skin epithelium after the initial infection, in most cases. Factors such as sunlight, shock, stress, fever, and hormonal changes can trigger a secondary or recurrent lesion such as herpes labialis.(1, 2) Herpes labialis appears primarily as a vesicle in the skin area around the oral cavity, lips, nose or the