Evaluating the impact of maternal vitamin D supplementation on sow performance: II. Subsequent growth performance and carcass characteristics of growing pigs1,2

Flohr, J. R.; Woodworth, J. C.; Bergstrom, J. R.; Tokach, Michael D.; Dritz, S. S.; Goodband, Robert D.; DeRouchey, Joel M.

doi:10.2527/jas.2016-0410

Cited by 24 publications

(21 citation statements)

References 23 publications

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“…In this study, no differences in serum vitamin D status were observed among all groups, which indicated that maternal vitamin D 3 didn't change the serum vitamin D concentration in later offspring pigs (at 150 days of age). A similar result was reported by Flohr et al (2016), who observed that maternal vitamin D influenced serum concentration in growing offspring pigs until 35 days post weaning. Flohr et al (2014) demonstrated that serum vitamin D 3 of weaned pigs (21 days of age) was not affected by maternal vitamin D status.…”

Section: Serum Biochemical Indexsupporting

confidence: 88%

Effects of maternal vitamin D₃ during pregnancy on FASN and LIPE mRNA expression in offspring pigs

Guo

Miao

et al. 2020

J. Agric. Sci.

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In this study, sows were fed 200 (LD), 800 (ND) and 3200 (HD) IU of vitamin D3/kg basal diet during pregnancy (from 41 d to birth), respectively. All their offspring pigs were fed the same vitamin D3 replete die. At 150 days of age, a total of 18 offspring pigs (six offspring pigs per maternal diet group, sex balance) were weighed and slaughtered to investigate effects of maternal vitamin D3 during pregnancy on fatty acids synthase (FASN) and hormone-sensitive lipase (LIPE) expression in offspring pigs. The results showed that LD offspring pigs had higher FASN mRNA expression and the ratio of FASN/LIPE mRNA expression in subcutaneous adipose tissue, as well as higher LIPE mRNA expression of longissimus dorsal muscle, whereas, had lower the ratio of FASN/LIPE mRNA expression in longissimus dorsal muscle compared with ND or HD offspring pigs, respectively. Meanwhile, LD offspring pigs had higher carcass fat, average backfat thickness (ABFT), serum insulin and leptin levels, lower intramuscular fat (IMF), serum free fatty acid and triglycerol levels compared with ND or HD offspring pigs. In addition, the ratio of FASN/LIPE mRNA expression was negatively correlated with IMF content, and positively correlated to carcass fat content and ABFT in offspring pigs. Meanwhile, FASN mRNA expression was positively correlated with carcass fat content, while negatively correlated with ABFT in offspring pigs. These results suggested that maternal vitamin D3 affected fat accumulation and meat quality by regulating FASN and LIPE mRNA expression in offspring pigs.

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Section: Serum Biochemical Indexsupporting

confidence: 88%

Effects of maternal vitamin D₃ during pregnancy on FASN and LIPE mRNA expression in offspring pigs

Guo

Miao

et al. 2020

J. Agric. Sci.

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“…Although, this might not be the case when considering how the increase in ADFI of pigs at these two ages would increase the daily consumption of total vitamin D 3 activity. Flohr et al (2016c) observed a quadratic effect of serum 25(OH)D 3 of nursery pigs on day 35 and a tendency on day 17 post weaning due to increasing maternal dietary supplementation of vitamin D 3 but noted these differences might be due to the increase in ADFI and total vitamin D 3 intake of the nursery pigs.…”

Section: Discussionmentioning

confidence: 94%

The effects of maternal dietary supplementation of cholecalciferol (vitamin D3) and 25(OH)D3 on sow and progeny performance1

Thayer

Nelssen

Langemeier

et al. 2019

Translational Animal Science

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Abstract A total of 69 sows (DNA Line 200 × 400) and their progeny were used to determine if feeding a combination of vitamin D3 and 25(OH)D3 influences neonatal and sow vitamin D status, muscle fiber morphometrics at birth and weaning, and subsequent growth performance. Within 3 d of breeding, sows were allotted to one of three dietary treatments fortified with 1,500 IU/kg vitamin D3 (CON), 500 IU/kg vitamin D3 + 25 μg/kg 25(OH)D3 (DL), or 1,500 IU/kg vitamin D3 + 50 μg/kg 25(OH)D3 (DH). When pigs were sacrificed at birth, there were no treatment effects for all fiber morphometric measures (P > 0.170), except primary fiber number and the ratio of secondary to primary muscle fibers (P < 0.016). Pigs from CON fed sows had fewer primary fibers than pigs from sows fed the DH treatment (P = 0.014), with pigs from sows fed DL treatment not differing from either (P > 0.104). Pigs from CON and DL fed sows had a greater secondary to primary muscle fiber ratio compared to pigs from DH sows (P < 0.022) but did not differ from each other (P = 0.994). There were treatment × time interactions for all sow and pig serum metabolites (P < 0.001). Therefore, treatment means were compared within the time period. At all time periods, sow serum 25(OH)D3 concentrations differed for all treatments with the magnitude of difference largest at weaning (P < 0.011), where serum 25(OH)D3 concentration was always the greatest when sows were fed the DH diet. At birth, piglets from DH fed sows had greater serum 25(OH)D3 concentrations than piglets from sows fed the DL treatment (P = 0.003), with piglets from sows fed CON treatment not differing from either (P > 0.061). At weaning, serum concentrations of 25(OH)D3 in piglets from all sow treatments were different (P < 0.001), with the greatest concentration in piglets from DH sows, followed by CON, and followed by DL. There were no treatment × time interactions for any of the metabolites measured in milk and no treatment or time main effects for 24,25(OH)2D3 concentration (P > 0.068). Colostrum collected within 12 h of parturition contained less (P = 0.001) 25(OH)D3 than milk collected on day 21 of lactation. Regardless of time, concentrations of 25(OH)D3 in milk were different (P < 0.030), with the largest 25(OH)D3 concentration from DH fed sows, followed by DL, and then CON. In conclusion, combining vitamin D3 and 25(OH)D3 in the maternal diet improves the vitamin D status of the dam and progeny and it increases primary muscle fiber number at birth.

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“…Recent studies have demonstrated that outdoor sun exposure does increase serum 25(OH)D concentrations in growing pigs and this can be more effective at increasing serum 25(OH)D than dietary supplementation [94,156]. demonstrated that dietary supplementation with 25(OH)D3 was more efficient than vitamin D3 supplementation at increasing serum 25(OH)D concentrations in sows, and resulted in faster growing piglets [157,158].…”

Section: Pigsmentioning

confidence: 99%

Vitamin D Metabolism and Profiling in Veterinary Species

2020

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The demand for vitamin D analysis in veterinary species is increasing with the growing knowledge of the extra-skeletal role vitamin D plays in health and disease. The circulating 25-hydroxyvitamin-D (25(OH)D) metabolite is used to assess vitamin D status, and the benefits of analysing other metabolites in the complex vitamin D pathway are being discovered in humans. Profiling of the vitamin D pathway by liquid chromatography tandem mass spectrometry (LC-MS/MS) facilitates simultaneous analysis of multiple metabolites in a single sample and over wide dynamic ranges, and this method is now considered the gold-standard for quantifying vitamin D metabolites. However, very few studies report using LC-MS/MS for the analysis of vitamin D metabolites in veterinary species. Given the complexity of the vitamin D pathway and the similarities in the roles of vitamin D in health and disease between humans and companion animals, there is a clear need to establish a comprehensive, reliable method for veterinary analysis that is comparable to that used in human clinical practice. In this review, we highlight the differences in vitamin D metabolism between veterinary species and the benefits of measuring vitamin D metabolites beyond 25(OH)D. Finally, we discuss the analytical challenges in profiling vitamin D in veterinary species with a focus on LC-MS/MS methods.

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Evaluating the impact of maternal vitamin D supplementation on sow performance: II. Subsequent growth performance and carcass characteristics of growing pigs1,2

Cited by 24 publications

References 23 publications

Effects of maternal vitamin D₃ during pregnancy on FASN and LIPE mRNA expression in offspring pigs

Effects of maternal vitamin D₃ during pregnancy on FASN and LIPE mRNA expression in offspring pigs

The effects of maternal dietary supplementation of cholecalciferol (vitamin D3) and 25(OH)D3 on sow and progeny performance1

Vitamin D Metabolism and Profiling in Veterinary Species

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Evaluating the impact of maternal vitamin D supplementation on sow performance: II. Subsequent growth performance and carcass characteristics of growing pigs1,2

Cited by 24 publications

References 23 publications

Effects of maternal vitamin D3 during pregnancy on FASN and LIPE mRNA expression in offspring pigs

Effects of maternal vitamin D3 during pregnancy on FASN and LIPE mRNA expression in offspring pigs

The effects of maternal dietary supplementation of cholecalciferol (vitamin D3) and 25(OH)D3 on sow and progeny performance1

Vitamin D Metabolism and Profiling in Veterinary Species

Contact Info

Product

Resources

About

Effects of maternal vitamin D₃ during pregnancy on FASN and LIPE mRNA expression in offspring pigs

Effects of maternal vitamin D₃ during pregnancy on FASN and LIPE mRNA expression in offspring pigs