Evaluating the interaction between 3'aQTL and alcohol consumption/smoking on anxiety and depression: 3'aQTL-by-environment interaction study in UK Biobank cohort

Introduction: Alcohol consumption has an impact on the frailty, but current research in China lacks a detailed classification of alcohol use. This study aimed to explore the relationship between different drinking patterns and frailty in older adults. Methodology: The data came from the 2018 Chinese Longitudinal Healthy Longevity Survey (CLHLS) study, which included older adults (aged ≧ 60). Their demographic data, drinking status, and frailty index were collected in CLHLS. Through logistic regression models to analyze the correlation between alcohol consumption and frailty. Results: A total of 14,931 participants were included in the analysis. The prevalence of frailty was 29.1%, 35.2%, and 14.9% among risk-free, past risky, and now risky drinkers, respectively. After adjusting for covariates, past risky drinking was a risk factor for frailty ( p = .003). Discussion: High-risk alcohol consumption is positively correlated with frailty. Prevention and reduction of risky drinking in older adults may help protect them from developing frailty.

show abstract

Association between the American Heart Association’s New Life’s Essential 8 Metrics and Depression Symptom in U.S General Adults, Finding from NHANES 2005-2018

Ruan,

Zhu,

et al. 2024

Front. Psychiatry

View full text Add to dashboard Cite

BackgroundThe American Heart Association (AHA) recently introduced a new metric for promoting cardiovascular health (CVH) called Life’s Essential 8 (LE8). However, there has been no investigation into the relationship between levels of LE8 and the risk of depression symptom. Therefore, our objective was to determine this association using a nationally representative sample of U.S adults.MethodsUtilizing cross-sectional data from the NHANES spanning the years 2005 to 2018, we computed scores for both overall CVH and individual LE8 components. The survey-weighted logistic regression models were conducted to determine whether LE8 was associated with depression symptom.ResultsA total of 25,357 adults aged 20 and above were included in the study, representing a population of 1,184 million non-institutionalized U.S residents. The study revealed that individuals with positive scores in both individual and total LE8 metrics were less likely to experience depressive symptoms compared to those with negative scores. Furthermore, a significant negative linear trend was observed, showing that as the overall number of favorable LE8 scores increased, the likelihood of depressive symptoms decreased.ConclusionAttaining a higher CVH score, as defined by the LE8, is strongly linked to a lower risk of experiencing depressive symptoms in adult residents of the U.S.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Evaluating the interaction between 3'aQTL and alcohol consumption/smoking on anxiety and depression: 3'aQTL-by-environment interaction study in UK Biobank cohort

Cited by 3 publications

References 54 publications

Lavender essential oil alleviates depressive-like behavior in alcohol-withdrawn rats: Insights from gut metabolites and hippocampal transcriptome analysis

Lavender essential oil alleviates depressive-like behavior in alcohol-withdrawn rats: Insights from gut metabolites and hippocampal transcriptome analysis

The Relationship Between Alcohol Consumption and Frailty Among Older Adults in China: Results From the Chinese Longitudinal Healthy Longevity Survey

Association between the American Heart Association’s New Life’s Essential 8 Metrics and Depression Symptom in U.S General Adults, Finding from NHANES 2005-2018

Contact Info

Product

Resources

About