Evaluating the Reliability and Reproducibility of the Ottawa Thoracic Morbidity and Mortality Classification System

Ivanovic, Jelena; Al-Hussaini, Ahmed; Alshehab, Derar; Threader, Jennifer; Villeneuve, Patrick J.; Ramsay, Tim; Maziak, Donna E.; Gilbert, Sébastien; Shamji, Farid M.; Sundaresan, R. Sudhir; Seely, Andrew J. E.

doi:10.1016/j.athoracsur.2010.10.035

Cited by 51 publications

(40 citation statements)

References 19 publications

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“…Concerning morbidity, on one hand, the number of complications per patient was analyzed. On the other hand, we distinguished major complications from minor complications according to the Ottawa Thoracic Morbidity and Mortality classification system recently proposed by Seely et al for severity of complications after thoracic surgery [10,11] (Appendix 1) and as described in Appendix 2. Mortality rates were collected at 30, 60 and 90 postoperative days for all patients regardless of hospital discharge status.…”

Section: Clinical Variables and Outcomesmentioning

confidence: 99%

Are postoperative consequences of neoadjuvant chemotherapy for non-small cell lung cancer more severe in elderly patients?

et al. 2012

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Section: Clinical Variables and Outcomesmentioning

confidence: 99%

Are postoperative consequences of neoadjuvant chemotherapy for non-small cell lung cancer more severe in elderly patients?

et al. 2012

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“…(13). Complications will be graded according to the thoracic morbidity and mortality classification system (38,39).…”

Section: Clinical Measuresmentioning

confidence: 99%

Patient reported outcomes following video assisted thoracoscopic (VATS) resection or stereotactic ablative body radiotherapy (SABR) for treatment of non-small cell lung cancer: protocol for an observational pilot study (LiLAC)

et al. 2017

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Background: Lung cancer is increasingly a disease of the elderly and frail population with a median age of 70 years at diagnosis. Therefore, consideration of the impact of interventions on health-related quality of life (HRQOL) and not only absolute survival is especially important. For non-small cell lung cancer (NSCLC), video-assisted thoracoscopic surgery (VATS) has been gaining popularity over the last few decades, replacing traditional open lobectomies. For high-risk patients who are not deemed suitable for surgery, stereotactic ablative body radiotherapy (SABR) provides a potentially curative alternative. However, little is known about how VATS and SABR affect HRQOL measured using patient reported outcome measures (PROMs). The LiLAC study (Life after Lung Cancer) aims to explore HRQOL following intervention with VATS or SABR using validated PROMs and to pilot the use of an online questionnaire system (QTool) in this setting. We hope the results will aid both patients and clinicians in decision making and improve the management of post-intervention problems.Methods: In total, 300 patients (150 VATS and 150 SABR) patients will be recruited over the study period.Patients will be approached prior to intervention and asked to complete baseline HRQOL questionnaires.They will be given access to the QTool online system and then in the 12 months following intervention will be asked to complete questionnaires (paper or online) at 4-time points. Answers will available for patients and clinicians to view throughout the study period. Clinical information (age, gender, co-morbidity, current medications and smoking status along with treatment-specific information) will also be collected. Primary outcome will be to detect changes of PROs (HRQOL and patient satisfaction) after VATS lung resections or SABR in early stage lung cancer patients. Secondary outcomes include correlation of patient's clinical data with HRQOL results to identify predictors of poor outcomes and exploration of patient and clinician views on the usefulness of QOL measurements.Discussion: (I) This first study will primarily compare multiple patients reported outcomes for 12 months after VATS lobectomy and SABR in early stages NSCLC patients. We will explore the acceptability of an online assessment of the HRQOL in NSCLC patients. (II) The study is also focused on the patients' opinion during the shared decision-making process, which has rarely been investigated in surgical lung cancer 2704 Pompili et al. LiLAC: life after lung cancer

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“…Major post-operative complications have been reported with VATS lobectomy [8], however, to our knowledge, no studies have addressed the impact of post-operative complications after lung cancer resection on patients' reported outcomes, and the effect it can have on recovery from surgery and return to baseline function and activates, and HRQOL in patients who might require further treatment in the form of chemotherapy. The Clavien surgical complication classification system has recently been validated in patients undergoing different thoracic surgery procedures [6].…”

Section: Introductionmentioning

confidence: 99%

“…Post-operative complications are commonly used for the assessment of quality of care in surgical practice [6] [7] and may also have an important role in functional recovery and HRQOL for patients undergoing surgical resection for lung cancer. Major post-operative complications have been reported with VATS lobectomy [8], however, to our knowledge, no studies have addressed the impact of post-operative complications after lung cancer resection on patients' reported outcomes, and the effect it can have on recovery from surgery and return to baseline function and activates, and HRQOL in patients who might require further treatment in the form of chemotherapy.…”

Section: Introductionmentioning

confidence: 99%

Effect of Surgical Complications on Quality of Life after Thoracoscopic Lobectomy for Lung Cancer

Gazala¹,

Johnson²,

Kutsogiannias³

et al. 2014

WJCS

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Background: Surgical resection is the main treatment for early stage lung cancer; the benefits of surgery, however, need to be weighed against possible complications and patients' quality of life. Methods: We performed a cohort study following patients after video assisted thoracoscopic lobectomy at our tertiary care center. Before surgery, health related quality of life was assessed using the SF-36, the QLQ30, QLQ13 and EQ5D questionnaires. Post-operatively health related quality of life was assessed at regular intervals (2, 4, 8 and 12 weeks). A research team assessed post-operative complications on a daily basis during the patients' hospital stay. Based on the Clavien classification system, the cohort was classified as experiencing high-grade (i.e., grade III or IV) complications or not. Changes in quality of life scores over the follow-up period were compared using linear regression with generalized estimating equations. Results: Between March and September 2011, 44 eligible patients were recruited into the study. The mean age was 65 (SD 8.7) years; 55% were male. The majority (n = 31; 71%) had no or low-grade complications. Patients experiencing high-grade complications reported significantly worse outcomes in the following domains of the SF-36: Global Health, Vitality, and Physical Functioning (p < 0.05 for all). On the QLQ 30 and QLQ 13, patients with high-grade complications had worse outcomes in the dyspnea, emotional function and cognitive function scales, as well as worse shoulder and chest pain, and financial difficulties (p < 0.05 for all). Conclusions: The severity of post-operative complications after video assisted thoracoscopic lobectomy negatively impacts patient centered outcomes postoperatively.

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Evaluating the Reliability and Reproducibility of the Ottawa Thoracic Morbidity and Mortality Classification System

Cited by 51 publications

References 19 publications

Are postoperative consequences of neoadjuvant chemotherapy for non-small cell lung cancer more severe in elderly patients?

Are postoperative consequences of neoadjuvant chemotherapy for non-small cell lung cancer more severe in elderly patients?

Patient reported outcomes following video assisted thoracoscopic (VATS) resection or stereotactic ablative body radiotherapy (SABR) for treatment of non-small cell lung cancer: protocol for an observational pilot study (LiLAC)

Effect of Surgical Complications on Quality of Life after Thoracoscopic Lobectomy for Lung Cancer

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