Evaluating the safety profile of semaglutide: an updated meta-analysis

Rivera, Frederick Berro; Arias-Aguirre, Eloise; Aguirre, Zedrick; Ybañez, Mc John C.; Rubia, Janos Marc M.; Galang, Danica Janine; Lumbang, Grace Nooriza; Ruyeras, Jade Monica Marie J.; Magalong, John Vincent; Pine, Polyn Luz; Amigo, John Andrew C.; Ansay, Marie Francesca M.; Zelenkov, Nenad; Thomas, Steve Samuel; Vijayaraghavan, Krishnaswami

doi:10.1080/03007995.2024.2383731

Current Medical Research and Opinion

2024

DOI: 10.1080/03007995.2024.2383731

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Evaluating the safety profile of semaglutide: an updated meta-analysis

Frederick Berro Rivera,

Eloise Arias-Aguirre,

Zedrick Aguirre

et al.

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Glucagon-like peptide-1 receptor agonists in peri-operative care

Paggers,

Mesotten,

Stragier

2024

European Journal of Anaesthesiology

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With the growing use of glucagon-like-peptide-1 (GLP-1) receptor (GLP-1R) agonists as anti-obesity medication it is becoming increasingly important to examine its consequences in the peri-operative period. GLP-1R agonists are known for their glucose-lowering and gastroparetic effects of which the latter causes some safety concerns regarding induction of anaesthesia, more specifically the risk of pulmonary aspiration. This article gathers the available evidence on this subject in addition to the already established guidelines. Current evidence makes us assume there is indeed an increased level of gastroparesis, but there are no studies to date with evidence of a presumed elevated risk of pulmonary aspiration. Future perspectives should focus on the actual risk of pulmonary aspiration and the possible implementation of ultrasound in the preoperative assessment.

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Glucagon-like peptide-1 receptor agonists in peri-operative care

Paggers,

Mesotten,

Stragier

2024

European Journal of Anaesthesiology

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show abstract

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Evaluating the safety profile of semaglutide: an updated meta-analysis

Cited by 1 publication

References 21 publications

Glucagon-like peptide-1 receptor agonists in peri-operative care

Glucagon-like peptide-1 receptor agonists in peri-operative care

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