Evaluating the therapeutic value of omega-3 polyunsaturated fatty acid supplementation on polycystic kidney disease and co-morbidities

The fatty acid profiles of mixed fermented milk and its anti-inflammation properties in an LPS-induced RAW264.7 cell model

“…26 They are both the precursors of lipid mediators that prevent inflammation or promote the elimination of inflammation and have potential anti-inflammatory activities in various inflammatory diseases. 27–29 At the same time, fatty acids are important signaling factors that can control inflammatory and anti-inflammatory responses connected with the balance of metabolic homeostasis. 26 However, the precursors of omega-3(n-3) fatty acids such as GLA, ALA, and EPA are insufficiently taken in through our daily diet.…”

The effects of omega-3 fatty acids on diabetic nephropathy: A meta-analysis of randomized controlled trials

“…Long-chain omega-3 polyunsaturated fatty acids, including eicosapentaenoic acid (EPA) and docosahexaenoic acids (DHA), have shown anti-inflammatory, antithrombotic properties and benefits on kidney function [9][10][11]. There is a number of clinical trials studying in various types of kidney diseases including IgA nephropathy [12], lupus nephritis [13,14] and polycystic kidney disease [15]. However, the information about the effects of omega-3 fatty acids on kidney function, particularly in diabetic kidney disease still lacks consensus.…”