2021
DOI: 10.1097/wco.0000000000000917
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Evaluating thunderclap headache

Abstract: Purpose of review Thunderclap headache (TCH) is an abrupt-onset of severe headache that needs to be thoroughly investigated because the most common secondary cause is subarachnoid hemorrhage (SAH). There has been no consensus guideline regarding the diagnostic workup. This review aims to provide an update on the evaluation of TCH. Recent findings The most important update in the 2019 American College of Emergency Physicians guideline for evaluation of a… Show more

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Cited by 8 publications
(5 citation statements)
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“…65 ) For patients presenting within 6 hours of headache onset who have no new neurological deficits, the lack of SAH on a noncontrast head CT is likely sufficient to exclude aSAH. 50–53 This question was evaluated in a 2016 meta-analysis in which 8907 patients were studied. Thirteen patients had a missed SAH on head CT performed within 6 hours, leading to a sensitivity of 98.7% and specificity of 99.9%.…”
Section: Clinical Manifestations and Diagnosis Of Asahmentioning
confidence: 99%
See 1 more Smart Citation
“…65 ) For patients presenting within 6 hours of headache onset who have no new neurological deficits, the lack of SAH on a noncontrast head CT is likely sufficient to exclude aSAH. 50–53 This question was evaluated in a 2016 meta-analysis in which 8907 patients were studied. Thirteen patients had a missed SAH on head CT performed within 6 hours, leading to a sensitivity of 98.7% and specificity of 99.9%.…”
Section: Clinical Manifestations and Diagnosis Of Asahmentioning
confidence: 99%
“…Another analysis estimated the sensitivity of CTA for ruptured aneurysms <3 mm at 61%. 64 Given the severe morbidity and potential mortality associated with a missed aSAH [50][51][52][53] This question was evaluated in a 2016 meta-analysis in which 8907 patients were studied. Thirteen patients had a missed SAH on head CT performed within 6 hours, leading to a sensitivity of 98.7% and specificity of 99.9%.…”
Section: Synopsismentioning
confidence: 99%
“…Other signs and symptoms that should be investigated are nausea, vomiting, visual disorders, hypertension (blood pressure > 140/90 mmHg), papilledema, confusional state, fever and focal neurological signs (paresthesia or weakness of arm or leg, facial weakness, speech disturbance, ataxic gait, paresis, abnormal eye movement, etc.) [99].…”
Section: Headachementioning
confidence: 99%
“…Thunderclap headache (TCH) is an abrupt onset of severe headache that needs to be thoroughly investigated because the most common secondary cause is subarachnoid hemorrhage (SAH) [99]. The first step to investigating an SAH is to perform a cerebral CT without contrast medium.…”
Section: Headachementioning
confidence: 99%
“…Thunderclap headache was first coined by Day and Raskin in the 1980s to describe a patient who developed an abrupt and severe headache that they considered to result from an unruptured aneurysm (38). In addition to primary HSA (13), numerous etiologies of thunderclap headache have been identified (3941), including SAH (42,43), RCVS (26), cervicocephalic artery dissection (44), CVT (45), cerebral infarction (43,46), intracerebral hemorrhage (43), meningitis (43), spontaneous intracranial hypotension (47), acute hypertensive crisis (48), pituitary apoplexy (49), aqueduct stenosis (50), giant cell arteritis (51), etc. Based on the ICHD-3 (2018) criteria for 4.4 Primary thunderclap headache (Table 4), not until all secondary causes and other ICHD-3 diagnoses have been demonstrably excluded can primary thunderclap headache be diagnosed (1).…”
Section: Introductionmentioning
confidence: 99%