Evaluation and characterization of <i>Pleurotus eryngii</i> extract-loaded chitosan nanoparticles as antimicrobial agents against some human pathogens

Acay, Hilal; Yıldırım, Ayfer; Güzel, Elif Erdem; Kaya, Nihat; Baran, Mehmet Fırat

doi:10.1080/10826068.2020.1765376

Cited by 19 publications

(18 citation statements)

References 46 publications

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“…According to the results of our previous study, SEM images showed that PE‐CSNP (particle size: 330.1 nm) have a more porosity network and smaller dimensions structure than CS alone. The same study also reported the nano‐encapsulated P. eryngii in CSNP would contribute to better bioavailability, as it has better‐controlled release compared to P. eryngii alone (Acay et al., 2020).…”

Section: Discussionmentioning

confidence: 91%

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The antioxidant and anti‐apoptotic potential of Pleurotus eryngii extract and its chitosan‐loaded nanoparticles against doxorubicin‐induced testicular toxicity in male rats

Güzel

Tektemur

et al. 2021

Andrologia

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This study was conducted to evaluate the protective role of Pleurotus eryngii extract (PE) and Pleurotus eryngii extract‐loaded chitosan nanoparticles (PE‐CSNP) against doxorubicin (DOX)‐induced testicular toxicity in rats. Male rats were divided into six groups: control (DMSO/ethanol), PE (200 mg/kg PE), PE‐CSNP (30 mg/kg PE‐CSNP), DOX (10 mg/kg DOX, a single dose, i.p), DOX+PE (10 mg/kg DOX+200 mg/kg PE) and DOX+PE‐CSNP (10 mg/kg DOX+30 mg/kg PE‐CSNP). PE and PE‐CSNP were administered by oral gavage every other day for 21 days. DOX‐treated rats showed histopathological impairment compared with the control group. There was an increase in the apoptotic index, caspase 3 (CASP3), BCL2‐associated X apoptosis regulator (BAX), dynamin‐related protein 1 (DRP1) expression and total oxidative status (TOS) in the DOX group, while mitofusin‐2 (MFN2), total antioxidative status (TAS) and serum testosterone levels of the DOX group reduced when compared with the other groups. PE and PE‐CSNP treatments provided significant protection against DOX‐induced oxidative stress by reducing TOS levels and increasing TAS levels. CASP3, BAX, apoptotic index and DRP1‐MFN2 expressions were restored by PE and PE‐CSNP. However, the PE‐CSNP showed higher antioxidant and anti‐apoptotic efficacy compared with PE. Thus, our results provide evidence that CSNP and PE could synergistically have a potent antioxidant and anti‐apoptotic therapy against DOX‐induced testicular damage in male rats.

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Section: Discussionmentioning

confidence: 91%

“…Nanoparticles were prepared by the method reported in our previous study (Acay et al., 2020). Firstly, 2 g of CS was dissolved in 1% CH 3 COOH, and 2 g of PE was added to the solution by stirring.…”

Section: Methodsmentioning

confidence: 99%

The antioxidant and anti‐apoptotic potential of Pleurotus eryngii extract and its chitosan‐loaded nanoparticles against doxorubicin‐induced testicular toxicity in male rats

Güzel

Tektemur

et al. 2021

Andrologia

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“…Pleurotus eryngii has medicinal properties. The FB extracts of this mushroom have potent antimicrobial activity against Escherichia coli, Staphylococcus aureus, Bacillus subtilis, and Candida albicans [4]. Polysaccharides and proteins in P. eryngii tissues have immunomodulating and antitumor properties [5,6].…”

Section: Introductionmentioning

confidence: 99%

Mushroom fruiting body yield and morphological characteristics from different strains of Pleurotus eryngii

Bandura¹,

S.²,

Alina³

et al. 2022

J Appl Biol Biotech

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Pleurotus eryngii is a new entrant into commercial cultivation, hence the need to optimize factors that affect yield and biological efficiency (BE) during cultivation. Two local isolates/strains, IBK 2032 and 2033, and a commercial strain, 2600, were studied for commercial cultivation suitability. Strain 2032 reached pinning 37.3 ± 0.9 days after inoculation, followed by 2033, 43.2 ± 1.2, and the last 2600 was 57.4 ± 4.8 days. Strains 2032, 2033, and 2600 attained the harvesting stage at 49.2 ± 6.1, 53.1 ± 3.2, and 68 ± 3.4 days, respectively, after inoculation. In fruiting body (FB) yield and BE, strain 2032 had 603.5 ± 9.2 g and 47.5% ± 6.6%, respectively, per bag; strain 2600 gave the least yield and BE. Strains 2032 and 2033 showed individual FB weight distribution values that displayed right-sided asymmetry, with coefficients of 1.73 and 1.31, respectively, whereas strain 2600 had a coefficient of 1.09. The cap diameter was largest in strain 2033 (59.7 mm), and the least (46.4 mm) was in strain 2600. Strain 2032 had the best results among all parameters measured, except for FB height. The results indicated yield, BE, and FB morphological characteristics in the local isolates that could support longer shelf life and consumer appeal.

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“…Therefore, chemical modification through composition and/or a crosslinking process is an alternative way to increase the mechanical resistance, reduce the hydrophobicity and stabilize chitosan in acidic environments. Also, mushrooms can be combined with chitosan to form a low-cost alternative composite material, due to their abundant and lignocellulosic combination that allows them to react with dye ions [11,12]. A lot of research has been conducted on dye adsorption using chitosan/chitosan combinations, such as chitosan [13], chitosan-vanadate films [14], a cellulose/chitosan composite [15], surface-modified chitosan [16], chitosan-based cryogel [17], a b-cyclodextrin-chitosan-based crosslinked adsorbent [18], chitosan/sodium alginate composite foams [19], and a biocomposite of chitosan, starch, and polyaniline [20].…”

Section: Introductionmentioning

confidence: 99%

Removal of the Anionic Dye Reactive Orange 16 by Chitosan/Tripolyphosphate/Mushroom

Yıldırım

2021

Chem Eng & Technol

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The green composite chitosan/tripolyphosphate/mushroom (C-TPP-PEE) was synthesized and evaluated for its adsorption performance of the dye Reactive Orange 16 (RO16), by using the batch technique. Fourier-transform infrared spectroscopy, thermogravimetric analysis, and field emission scanning electron microscopy were employed to characterize the C-TPP-PEE. The maximum adsorption capacity of the RO16 dye for batch adsorption was determined as 736 mg g -1 . The experimental kinetic data at equilibrium was found to be best fitted to the pseudo-second-order kinetic model. The results showed that the adsorption isotherm was best correlated to the Langmuir model. The thermodynamic data indicated that the adsorption process was spontaneous, favorable, and endothermic.

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Evaluation and characterization of Pleurotus eryngii extract-loaded chitosan nanoparticles as antimicrobial agents against some human pathogens

Cited by 19 publications

References 46 publications

The antioxidant and anti‐apoptotic potential of Pleurotus eryngii extract and its chitosan‐loaded nanoparticles against doxorubicin‐induced testicular toxicity in male rats

The antioxidant and anti‐apoptotic potential of Pleurotus eryngii extract and its chitosan‐loaded nanoparticles against doxorubicin‐induced testicular toxicity in male rats

Mushroom fruiting body yield and morphological characteristics from different strains of Pleurotus eryngii

Removal of the Anionic Dye Reactive Orange 16 by Chitosan/Tripolyphosphate/Mushroom

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