Evaluation and prediction of the shape of gas chromatographic peaks

Moretti, Paolo; Vezzani, S.; Garrone, Edoardo; Castello, Gianrico

doi:10.1016/j.chroma.2004.03.039

Cited by 14 publications

(6 citation statements)

References 20 publications

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“…The key parameters of GC-MS (such as peak area and peak height) are highly affected by the ow rate changes of the carrier gas. Lower carrier gas ow is bene cial to compound separation, while higher gas ow is helpful to getting a better shape of chromatographic peaks (Moretti et al 2004).…”

Section: Optimization Of Gc×gc Conditionmentioning

confidence: 99%

WITHDRAWN: Development of a quantitative screening method for 100 pesticides in plant- derived foods using comprehensive two-dimensional gas chromatography time-of-flight mass spectrometry

Wang

Jiang

Almvik

et al. 2022

Preprint

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This study applied comprehensive two-dimensional gas chromatography time-of-flight mass spectrometry (GC×GC-TOF-MS) for the analysis of 100 pesticides (77 organophosphorus and 23 organochlorines) in six typical plant matrices with high protein, starch, acid, or oil content. Different sorbents were evaluated in the clean-up step of the QuEChERS method, and the optimized sorbent combinations were obtained for each individual matrix. Good linearity of the calibration curves of matrix-matched was obtained (R2 ≥ 0.9853). The mean recoveries and relative standard deviations at fortification levels of 10 and 50 μg/kg ranged from 72.6 to 117.5% and 0.1 to 19.9%, respectively. Phenolic antioxidants, glycosides, phosphorus esters, linoleic acid, unsaturated fatty acids, and other interferences in individual plant matrix were identified. The results demonstrated that GC×GC-TOF-MS is helpful in separation of the co-eluted pesticides and the identification of interferences in complex plant matrices.

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Section: Optimization Of Gc×gc Conditionmentioning

confidence: 99%

WITHDRAWN: Development of a quantitative screening method for 100 pesticides in plant- derived foods using comprehensive two-dimensional gas chromatography time-of-flight mass spectrometry

Wang

Jiang

Almvik

et al. 2022

Preprint

View full text Add to dashboard Cite

show abstract

“…The key parameters of GC–MS (such as peak area and peak height) are highly affected by the flow rate changes of the carrier gas. Lower carrier gas flow is beneficial to compound separation, while higher gas flow is helpful in getting a better shape of chromatographic peaks . Meanwhile, it should be noted that the high vacuum system of MS does not allow for more carrier gas input, and a higher flow rate is detrimental to the vacuum system and detection performance .…”

Section: Resultsmentioning

confidence: 99%

“…Lower carrier gas flow is beneficial to compound separation, while higher gas flow is helpful in getting a better shape of chromatographic peaks. 18 Meanwhile, it should be noted that the high vacuum system of MS does not allow for more carrier gas input, and a higher flow rate is detrimental to the vacuum system and detection performance. 19 In this study, the separation performance for all target compounds at different carrier gas flow rates (0.8, 1.0, 1.2, 1.5, and 1.8 mL/min) was tested, and it was found that the rate of 1.0 mL/min could achieve the best separation and peak shape.…”

Section: Optimization Of Ion Sourcementioning

confidence: 99%

Development of a Quantitative Screening Method for 100 Pesticides in Plant-Derived Foods Using Comprehensive Two-Dimensional Gas Chromatography Time-of-Flight Mass Spectrometry

Wang,

Jiao,

Almvik

et al. 2023

ACS Agric. Sci. Technol.

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This study applied comprehensive two-dimensional gas chromatography time-of-flight mass spectrometry (GC × GC-TOF-MS) for the analysis of 100 pesticides (77 organophosphorus and 23 organochlorines) in six typical plant matrices with high protein, starch, acid, or oil content. Different sorbents were evaluated in the clean-up step of the QuEChERS method, and optimized sorbent combinations were obtained for each individual matrix. Good linearity of the calibration curves of matrix-matched was obtained (R 2 ≥ 0.9853). The mean recoveries and relative standard deviations at fortification levels of 10 and 50 μg/kg ranged from 72.6 to 117.5 and 0.1 to 19.9%, respectively. Phenolic antioxidants, glycosides, phosphorus esters, linoleic acid, unsaturated fatty acids, and other interferences in the individual plant matrix were identified. The results demonstrated that GC × GC-TOF-MS is helpful in the separation of the co-eluted pesticides and the identification of interferences in complex plant matrices.

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“…On the other side, there are a lot of publications devoted to the description and modeling the distortions of the shapes of chromatographic peaks influenced by different factors, including sample size and overloading the column (see, e.g. [30][31][32][33][34][35][36]). However, such distortions have never been considered in relation to the dependence of retention indices of analytes vs. the ratio of their amounts to the quantities of reference compounds.…”

Section: Interpretation Of the Dependence Ri( ) By Computer Modelingmentioning

confidence: 99%

Dependence of chromatographic retention indices on a ratio of amounts of target and reference compounds

Зенкевич

Ukolova

2012

Journal of Chromatography A

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Evaluation and prediction of the shape of gas chromatographic peaks

Cited by 14 publications

References 20 publications

WITHDRAWN: Development of a quantitative screening method for 100 pesticides in plant- derived foods using comprehensive two-dimensional gas chromatography time-of-flight mass spectrometry

WITHDRAWN: Development of a quantitative screening method for 100 pesticides in plant- derived foods using comprehensive two-dimensional gas chromatography time-of-flight mass spectrometry

Development of a Quantitative Screening Method for 100 Pesticides in Plant-Derived Foods Using Comprehensive Two-Dimensional Gas Chromatography Time-of-Flight Mass Spectrometry

Dependence of chromatographic retention indices on a ratio of amounts of target and reference compounds

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