Evaluation and Prevention of Changes in Oral Cavity Through Cytotoxic Effect of the Chemical Components from Dental Materials

Abstract

The use of a suitable biological material, represented by the normal cell culture cell line RM, consisting of monkey kidney cells or of suitable experimental models allow the investigation of the reactivity of the cell protein synthesis process (illustrated by the total protein content of the cell cultures aged 72 hours, after a 48-hour treatment), cell proliferation (expressed by the evolution of the total cell number during cell culture development), cell viability (characterized by the dynamics of the dead / living cells ratio), cell apoptosis and cell culture development. Alteration of these processes reflects the cytotoxic impact of some products on protein synthesis, mitosis, cell apoptosis and cell viability.