“…Earlier studies focused on patient characteristics and identified several variables that were associated with regret in their patient populations. These variables include psychological variables (11,22,23), such as previous history of depression (15,26), character pathology (26) or personality disorder (5,15), history of psychotic disorder (15,28), overactive temperament (26), negative self-image (26) or other psychopathology (15,19,26), as well as various social or familial factors that include history of family trauma (19,29), poor family support (5,11,15,28), belonging to a non-core group (28), previous marriage (15,19), and biological parenthood (15,19). Landen et al identified poor family support as the most important variable predicting future postoperative regret in transgender men and women undergoing gender-affirming surgery in Sweden between 1972-1992 (28).…”