Évaluation de la prise en charge des états de mal épileptiques convulsifs en milieu tropical

Cisse, Fodé Abass; Tassiou, Nana Rahamatou; Barry, Souleymane; Sakadi, Foksouna; Bah, Aissatou Kenda; Nyassinde, Japhari; Cissé, A.

doi:10.1016/j.neurol.2017.01.023

Cited by 3 publications

(16 citation statements)

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“…This hospital-based study on CSE represents the first interest on this topic in our setting. The prevalence of 2.03% found is lower than the prevalence reported in other Sub-Saharan African (SSA) countries [1] , [2] , [9] . Our study was carried out in an emergency department receiving patients from different specialties, whereas other SSA studies had been carried out exclusively in neurology departments or in ICU.…”

Section: Discussionmentioning

confidence: 74%

“…Brain imaging had been performed in 92.4% of patients in this study. Data obtained in other developing countries found 66% in Guinea Conakry and 45.4% in Ethiopia [2] , [7] . The Douala general hospital has a radiology department with a CT scan and an MRI which operates 24/7.…”

Section: Discussionmentioning

confidence: 83%

“…Cissé et al ., and Gams et al . reported prolonged seizures (more than 30 min) in the majority of cases [2] , [5] . The permanent presence of a critical care physician could contribute to lower percentage of prolonged seizures in the MSED of the Douala General Hospital.…”

Section: Discussionmentioning

confidence: 99%

“…In Africa, few epidemiological data are available on status epilepticus (SE). Studies carried out in sub-Saharan Africa have found a hospital-based prevalence varying between 5.28 and 10.86% [1] , [2] . Clinically there are two presentations: the convulsive SE (CSE) and the non-convulsive SE (NCSE) [3] .…”

Section: Introductionmentioning

confidence: 99%

“…The commonest causes are: cerebrovascular accidents, antiseizure medications (ASM) disruptions, and central nervous system (CNS) infections [4] . In Africa, the most frequent etiologies are vascular and infectious [2] , [5] , [6] , [7] . Current management recommendations are based on studies from developed countries [8] .…”

Section: Introductionmentioning

confidence: 99%

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Convulsive status epilepticus in an emergency department in Cameroon

Massi

Owona

Magnerou

et al. 2021

Epilepsy & Behavior Reports

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Section: Discussionmentioning

confidence: 74%

Section: Discussionmentioning

confidence: 83%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Convulsive status epilepticus in an emergency department in Cameroon

Massi

Owona

Magnerou

et al. 2021

Epilepsy & Behavior Reports

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Etiological Spectrum of Status Epilepticus in Ouagadougou, Burkina Faso: A Prospective Cross-sectional Multicenter Hospital Study

Lompo¹,

Somé²,

Dakouré³

et al. 2021

CNN

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Introduction: In sub-Saharan Africa, cerebrovascular aetiologies of status epilepticus (SE) are on the rise alongside infectious brain lesions. The aim of our study was to describe the etiologic spectrum of SE in Ouagadougou, Burkina Faso, in a high risk SE setting. Patients and methods: This is a prospective, cross-sectional, descriptive, multicenter and hospital study of patients hospitalized consecutively in the university hospitals of the city of Ouagadougou, in Burkina Faso, from 01/01/2015 to 12/31/2019, for SE. The sociodemographic, clinical, paraclinical (biological, critical and / or intercritical EEG, neuroradiological) characteristics and the aetiological data of the patients were analyzed using the Epi-info 7.2.1.0 software: calculations of numbers, frequencies, averages. The significance rate was set at 0.05. Results: 91 patients hospitalized for SE were collected, with a male predominance (73.62%). The mean age was 36.6 years +/-24.5 years (2 days and 86 years); 25 patients (27.5%) already had known epilepsy. Generalized tonic-clonic SE from the start and focal SE with convulsive bilateralization were the most common seizure types with 46 cases (50.5%) and 27 cases (29.7%), respectively. The average duration of an EME episode was 18 hours +/-31 (5 minutes -6 days). On admission, a focused motor deficit with 36 cases (46.7%) and fever in 28 patients (30.8%) were the main clinical signs; hyperleukocytosis with 23 cases (25.3) and anemia with 22 cases (24.2%), were the main laboratory abnormalities. On cerebral CT scan, sequelae with 33 cases (51.6%), acute stroke with 14 cases (21.9%) and acute meningoencephalitis with 8 cases (12.5%), were the most frequent. SEs symptomatic of acute brain disease, with 61 cases (67%), were dominated by infectious etiologies with 30 cases (33%) and acute strokes with 16 cases (17.6%). Among the non-acute or sequelae SEs of etiology, the sequelae of traumatic brain injury with 10 cases (11%) and the sequelae of stroke with 8 cases (8.8%) were the most represented. Conclusion: The aetiologies of SE are dominated in the Ouagadougou CHUs by CNS infections, acute or sequelae strokes and cranio-encephalic trauma. The fight against infectious diseases and the prevention of vascular risk factors will help reduce the frequency and severity of EMEs.

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Predictors of in-hospital mortality among patients with status epilepticus in Lubumbashi, Democratic Republic of the Congo: A retrospective study

Bugeme,

Mukuku,

Ditend

et al. 2024

Adv. Gen. Pract. Med.

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Objective: Status Epilepticus (SE) is a condition characterized by an epileptic seizure that persists long enough or recurs at sufficiently short intervals to create a fixed and lasting epileptic condition. The objective of this study was to determine the prevalence and to identify predictors of in-hospital death among SE patients in Lubumbashi, Democratic Republic of the Congo (DRC). Methods: We conducted a retrospective study from January 2020 to December 2022. Results: Out of 3,006 patients admitted to the neurology department of the University Clinics of Lubumbashi, 97 presented with SE (i.e., a hospital prevalence of 3.23%). The mean age of the patients was 38.38±14.74 years, and men represented 77.3% of the cases. Epileptic patients represented 21.65% of the cases and 66.7% of them were on antiepileptic drugs (AEDs). Seizures were generalized in 72.16% of the patients. Seizures lasted 30 minutes or more in 50.52% of the cases. The most frequent etiologies were strokes, followed by central nervous system (CNS) infections. In-hospital mortality was 24.74% and the predictors of this mortality were CNS infections (adjusted OR = 22.34 [2.69-222.65]; p = 0.0006) and seizures lasting ≥ 30 minutes (adjusted OR = 10.98 [2.89-62.70]; p<0.0001). Conclusion: SE is a major neurological emergency requiring early and multidisciplinary management to preserve the vital prognosis because, without treatment, SE causes important neurological complications and even death. The present study found a mortality of 24.74% which was associated with seizure duration of more than 30 minutes as well as with infectious etiologies.

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Évaluation de la prise en charge des états de mal épileptiques convulsifs en milieu tropical

Cited by 3 publications

References 0 publications

Convulsive status epilepticus in an emergency department in Cameroon

Convulsive status epilepticus in an emergency department in Cameroon

Etiological Spectrum of Status Epilepticus in Ouagadougou, Burkina Faso: A Prospective Cross-sectional Multicenter Hospital Study

Predictors of in-hospital mortality among patients with status epilepticus in Lubumbashi, Democratic Republic of the Congo: A retrospective study

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