Évaluation du pronostic de l’encéphalopathie précoce du nouveau-né à terme avant l’avènement de l’hypothermie

Jadas, V.; Brasseur‐Daudruy, M.; Chollat, Clément; Pellerin, L.; Devaux, A M; Marret, Stéphane; Haute-Normandie, et le de périnatalité de réseau

doi:10.1016/j.arcped.2013.11.007

Cited by 4 publications

(2 citation statements)

References 26 publications

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“…T1WI could provide essential information for the diagnosis and depicting typical MRI features of hypoxic-ischemic injury (3,5–6). The imaging pattern of HIE has been classified into three types (4,23); parasagittal lesions, involving cortico-subcortical regions, profound lesions located in the basal ganglia or thalamus, and multi-cystic encephalomalacia.…”

Section: Discussionmentioning

confidence: 99%

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Early identification of hypoxic-ischemic encephalopathy by combination of magnetic resonance (MR) imaging and proton MR spectroscopy

Guo

De-hang

et al. 2016

Experimental and Therapeutic Medicine

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Brain damage following a perinatal hypoxic-ischemic encephalopathy (HIE) can be diagnosed by different techniques. The aim of the present study was to combine magnetic resonance (MR) imaging with proton MR spectroscopy in HIE diagnosis and to evaluate their correlation with outcome. A prospective observational cohort study was performed between February 2012 and February 2013. Consecutive newborns, 24 full-term neonates with HIE (mild to moderate and severe group) and 5 normal neonates, were included. Two sequential MR studies were performed; a conventional MR imaging for observation in T1 weighted image (WI) and T2WI, and proton MR spectroscopy for observation in the left or right basal ganglia and thalamus. MR images were assessed and scored by two neuroradiologists who were blinded to the clinical condition of the infants. The mild to moderate group (n=13) and severe group (n=11) were similar in the visualization of punctate hyperintensity lesions on T1WI and brain edema on T2WI. The differences of N-acetylaspartate/creatine (Cr), choline/Cr and lactate/Cr in the basal ganglia and thalamus in the HIE group were significantly different (P<0.05) compared with the control group, while no significant difference was identified between the mild to moderate and severe group (P>0.05). In conclusion, MR spectroscopy is a complementary tool for the diagnosis of HIE.

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Section: Discussionmentioning

confidence: 99%

“…It is understood that MRI serves an increasing important role for imaging the neonatal brain (3–6). However, proton MR spectroscopy has been developed for clinical use.…”

Section: Introductionmentioning

confidence: 99%

Early identification of hypoxic-ischemic encephalopathy by combination of magnetic resonance (MR) imaging and proton MR spectroscopy

Guo

De-hang

et al. 2016

Experimental and Therapeutic Medicine

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Place de l’anoxie et du traitement par hypothermie dans l’encéphalopathie néonatale précoce du nouveau-né à terme

Marret

Jadas

Kieffer

et al. 2014

Archives de Pédiatrie

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Early MRI in neonatal hypoxic-ischaemic encephalopathy treated with hypothermia: Prognostic role at 2-year follow-up

Charon

Proisy

Bretaudeau

et al. 2016

European Journal of Radiology

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, et al.. Early MRI in neonatal hypoxic-ischaemic encephalopathy treated with hypothermia: Prognostic role at 2-year follow-up.European Journal of Radiology, Elsevier, 2016, 85 (8), pp.1366-1374. 10.1016/j.ejrad.2016 CONFLICTS OF INTERESTThe authors have no conflict of interest to declare. Conflict of InterestEarly MRI in neonatal hypoxic-ischaemic encephalopathy treated with hypothermia: prognostic role at 2-year follow-up

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Évaluation du pronostic de l’encéphalopathie précoce du nouveau-né à terme avant l’avènement de l’hypothermie

Cited by 4 publications

References 26 publications

Early identification of hypoxic-ischemic encephalopathy by combination of magnetic resonance (MR) imaging and proton MR spectroscopy

Early identification of hypoxic-ischemic encephalopathy by combination of magnetic resonance (MR) imaging and proton MR spectroscopy

Place de l’anoxie et du traitement par hypothermie dans l’encéphalopathie néonatale précoce du nouveau-né à terme

Early MRI in neonatal hypoxic-ischaemic encephalopathy treated with hypothermia: Prognostic role at 2-year follow-up

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