In the last decades, several studies aimed at assessing some specified aspects of visual comfort characterizing the relationship between the human needs and the light environment, such as an available amount of light, light uniformity, light quality in rendering colors, and predicting the risk of glare for space occupants. For each of them, a (still growing) number of indices and metrics have been proposed in literature and standards. In the present work, they are described, categorized according to common features, and finally discussed. As in the case of long-term thermal comfort indices, such visual comfort indices and their summation over a specified calculation period might be used for driving optimization processes to support a more conscious integrated design of buildings. To that purpose, the choice among the available visual comfort indices needs to be informed by an analysis of their features and implications. We present recommendations for use, and suggest areas where improvement is needed for their use in optimization processes to support buildings' design.